88575-6Onchocerca sp IgG4 Ab [Presence] in Serum by ImmunoassayActive
Part Descriptions
LP14830-1 Onchocerca sp
Onchocerca is a genus of nematode (roundworm) that includes O. volvulus, the causative agent of the human disease known as River Blindness. River blindness results in vision impairment and can also cause skin disease and debilitating itching. Onchocerciasis is the second-leading infectious cause of blindness in humans. [https://www.cdc.gov/parasites/onchocerciasis/index.html] Other species of Onchocerca include O. lupi, which can cause disease in dogs, cats, and humans, O. gutturosa and O. lienalis, which affect cattle, and O. cervicalis, which affects horses.
Source: Regenstrief LOINC
LP32397-9 Ab.IgG4
IgG4 is the least common subtype of IgG, and it has a variety of functions. In the context of allergic disease it is thought to have an immune-inhibitory role in preventing anaphylaxis and is commonly known as a "blocking" antibody. IgG4 binding to an allergen can compete with IgE-mediated binding, thereby inhibiting the activation of mast cells and basophils and IgE-mediated presentation to T-cells. Measuring IgG4 and its ratio to IgE has a role in monitoring allergen specific immunotherapy [PMID:26023323]. IgG4 is also thought to have a role in autoimmunity and be involved in a less defined entity known as IgG4-Related Disease, a chronic immune-mediated fibroinflammatory disorder that often manifests with tumor-like masses .[https://www.merckmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/igg4-related-disease/igg4-related-disease]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Onchocerca sp Ab.IgG4
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- IA
Additional Names
- Short Name
- Onchocerca IgG4 Ser Ql IA
- Display Name
- Onchocerca sp IgG4 IA Ql (S)
- Consumer Name Alpha
- Onchocerca sp IgG4 antibody, Blood
Example Answer List LL744-4
Source: Regenstrief Institute
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Detected | LA11882-0 | ||
| Not detected | LA11883-8 |
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.64
- Last Updated
- Version 2.64
- Order vs. Observation
- Both
Language Variants Get Info
- zh-CNChinese (China)
- 盘尾属 抗体.IgG4:
存在情况或阈值: 时间点: 血清: 序数型: 免疫测定法 - nl-NLDutch (Netherlands)
- Onchocerca sp. As.IgG4:
aanwezigheid: moment: serum: ordinaal: immunoassay - et-EEEstonian (Estonia)
- Onchocerca sp antikehad.IgG4:
PrThr: Pt: S: Ord: IA - fr-BEFrench (Belgium)
- Onchocerca sp Anticorps. IgG4:
PrThr: Temps ponctuel: Sérum: Ordinal: IA - fr-CAFrench (Canada)
- Onchocerca sp , IgG4:
Présence-Seuil: Temps ponctuel: Sérum: Ordinal: IA - fr-FRFrench (France)
- Onchocerca Ac IgG4:
Présence/Seuil: Ponctuel: Sérum: Qualitatif: Immunoanalyse - it-ITItalian (Italy)
- Onchocerca sp Ab.IgG4:
PrThr: Pt: Siero: Ord: IA - ru-RURussian (Russian Federation)
- Onchocerca sp Ат.IgG4:
PrThr: ТчкВрм: Сыв: Пор: IA - es-MXSpanish (Mexico)
- Onchocerca sp Ab.IgG4:
Presencia o umbral: Punto temporal: Suero: Ordinal: Inmunoensayo - es-ESSpanish (Spain)
- Onchocerca sp IgG4:
PrThr: Punto temporal: Suero: Ord: IA - tr-TRTurkish (Turkey)
- Onchocerca sp Ab.IgG4:
MevcEşik: Zmlı: Ser: Srl: İA
LOINC FHIR® API Example - CodeSystem Request Get Info
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=88575-6
LOINC Copyright
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