LOINC
Version 2.72

88575-6Onchocerca sp IgG4 Ab [Presence] in Serum by ImmunoassayActive

Part Descriptions

LP14830-1   Onchocerca sp
Onchocerca is a genus of nematode (roundworm) that includes O. volvulus, the causative agent of the human disease known as River Blindness. River blindness results in vision impairment and can also cause skin disease and debilitating itching. Onchocerciasis is the second-leading infectious cause of blindness in humans. [https://www.cdc.gov/parasites/onchocerciasis/index.html] Other species of Onchocerca include O. lupi, which can cause disease in dogs, cats, and humans, O. gutturosa and O. lienalis, which affect cattle, and O. cervicalis, which affects horses. Source: Regenstrief LOINC

LP32397-9   Ab.IgG4
IgG4 is the least common subtype of IgG, and it has a variety of functions. In the context of allergic disease it is thought to have an immune-inhibitory role in preventing anaphylaxis and is commonly known as a "blocking" antibody. IgG4 binding to an allergen can compete with IgE-mediated binding, thereby inhibiting the activation of mast cells and basophils and IgE-mediated presentation to T-cells. Measuring IgG4 and its ratio to IgE has a role in monitoring allergen specific immunotherapy [PMID:26023323]. IgG4 is also thought to have a role in autoimmunity and be involved in a less defined entity known as IgG4-Related Disease, a chronic immune-mediated fibroinflammatory disorder that often manifests with tumor-like masses .[https://www.merckmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/igg4-related-disease/igg4-related-disease] Source: Regenstrief LOINC

Fully-Specified Name

Component
Onchocerca sp Ab.IgG4
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
IA

Additional Names

Short Name
Onchocerca IgG4 Ser Ql IA
Display Name
Onchocerca sp IgG4 IA Ql (S)
Consumer Name Alpha
Onchocerca sp IgG4 antibody, Blood

Example Answer List LL744-4

Source: Regenstrief Institute

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.64
Last Updated
Version 2.64
Order vs. Observation
Both

Language Variants Get Info

zh-CNChinese (China)
盘尾属 抗体.IgG4:存在情况或阈值:时间点:血清:序数型:免疫测定法
nl-NLDutch (Netherlands)
Onchocerca sp. As.IgG4:aanwezigheid:moment:serum:ordinaal:immunoassay
et-EEEstonian (Estonia)
Onchocerca sp antikehad.IgG4:PrThr:Pt:S:Ord:IA
fr-BEFrench (Belgium)
Onchocerca sp Anticorps. IgG4:PrThr:Temps ponctuel:Sérum:Ordinal:IA
fr-CAFrench (Canada)
Onchocerca sp , IgG4:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:IA
fr-FRFrench (France)
Onchocerca Ac IgG4:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunoanalyse
it-ITItalian (Italy)
Onchocerca sp Ab.IgG4:PrThr:Pt:Siero:Ord:IA
ru-RURussian (Russian Federation)
Onchocerca sp Ат.IgG4:PrThr:ТчкВрм:Сыв:Пор:IA
es-MXSpanish (Mexico)
Onchocerca sp Ab.IgG4:Presencia o umbral:Punto temporal:Suero:Ordinal:Inmunoensayo
es-ESSpanish (Spain)
Onchocerca sp IgG4:PrThr:Punto temporal:Suero:Ord:IA
tr-TRTurkish (Turkey)
Onchocerca sp Ab.IgG4:MevcEşik:Zmlı:Ser:Srl:İA

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=88575-6