LOINC
Version 2.67

88881-8Smith extractable nuclear D Ab [Presence] in Serum by Line blotActive

Term Description

This test was created for, but not limited to, the INNO-LIA ANA Update test kit, which is a line immunoassay for the detection and identification of thirteen antinuclear antibodies (ANA) in human serum to aid in the diagnosis of connective tissue disorders.
Source: Regenstrief LOINC

Part Description

LP71718-8   Smith extractable nuclear D
Smith extractable nuclear D (Sm-D) antibodies target Sm-D proteins, which are among the 7 Sm proteins (B/B', D1, D2, D3, E, F, G) that constitute the common core of U1, U2, U4 and U5 small nuclear ribonucleoprotein (snRNP). SmD is a mixture of D1, D2, and D3. Of these, D1 and D3 are among those more frequently targeted by Anti-Sm antibodies. [PMID: 15804705] Anti-Sm antibodies are a type of extractable nuclear antigens (ENA) antibodies that cause a variety of autoimmune diseases, including systemic lupus erythematosus (SLE).[PMCID: PMC119916] Source: Regenstrief LOINC

Fully-Specified Name

Component
Smith extractable nuclear D Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
Line blot

Additional Names

Short Name
ENA SM-D Ab Ser Ql Line blot
Display Name
Smith extractable nuclear D Ab Line blot Ql (S)

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.64
Last Updated
Version 2.64
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Panels

LOINC Long Common Name
88883-4 Autoimmune connective tissue Ab panel - Serum by Line blot

Member of these Groups

LG50059-1 Smith extractable nuclear D Ab|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (CHINA)
Smith 可提取性核 D 抗体:存在情况或阈值:时间点:血清:序数型:线点印迹法
nl-NLDutch (NETHERLANDS)
Smith extraheerbare nucleaire D As:aanwezigheid:moment:serum:ordinaal:lijnblot
fr-CAFrench (CANADA)
Smith nucléaire soluble D , Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Immunoessai sur bandelette
fr-FRFrench (FRANCE)
Sm D anticorps:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Blot en ligne
de-ATGerman (AUSTRIA)
SmD-Antikörper qual. IB
es-ESSpanish (SPAIN)
Smith nuclear extraíble C Anticuerpos:PrThr:Punto temporal:Suero:Ord:Line blot

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=88881-8