LOINC
Version 2.72

89314-9Bacterial 23S rRNA gene azithromycin resistance mutation [Presence] by Molecular methodActive

Term Description

This term detects mutations in the 23S rRNA gene responsible for bacterial resistance to azithromycin.
Source: Regenstrief LOINC

Part Description

LP266750-1   Bacterial 23S rRNA gene azithromycin resistance mutation
Bacterial resistance to macrolide drugs has increased in conjunction with their heavy use in both medicine and animal husbandry. While there are a number of mechanisms bacteria use to resist the efficacy of drug treatment, the one used by macrolides is to bind to the large 50S subunit of the bacterial ribosome and interfere with protein synthesis. Changes of specific nucleotides in the 23S rRNA inside the large ribosomal unit are the root cause of many instances of bacterial resistance to macrolides.[PMID:11120937] Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Regenstrief LOINC, Azithromycin (Wikipedia)

Fully-Specified Name

Component
Bacterial 23S rRNA gene azithromycin resistance mutation
Property
PrThr
Time
Pt
System
Isolate/Specimen
Scale
Ord
Method
Molgen

Additional Names

Short Name
Bact 23S rRNA azith res mut Islt/Spm Ql
Display Name
Bacterial 23S rRNA gene azithromycin resistance mutation Molgen Ql (Islt/Spec)
Consumer Name Alpha
Bacterial 23S rRNA gene azithromycin resistance mutation

Preferred Answer List LL744-4

Source: Regenstrief Institute

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.64
Last Updated
Version 2.65
Change Reason
Updated System from "Isolate" according to the new, more sustainable model for LOINC molecular resistance terms [Approved by LOINC Laboratory Committee in June 2018].
Order vs. Observation
Both

Language Variants Get Info

zh-CNChinese (China)
细菌 23S rRNA 基因阿奇霉素耐药性突变:存在情况或阈值:时间点:分离株/标本:序数型:分子遗传学类实验室方法
nl-NLDutch (Netherlands)
bacteriële azitromycineresistentie 23S-rRNA-genmutatie:aanwezigheid:moment:isolaat of monster:ordinaal:moleculair genetisch onderzoek
fr-FRFrench (France)
Bactérie ARNr 23S gène mutation de résistance à l'azithromycine:Présence/Seuil:Ponctuel:Isolat/échantillon:Qualitatif:Biologie moléculaire
it-ITItalian (Italy)
Gene batterico 23S rRNA, mutazione resistenza a azitromicina:PrThr:Pt:Isolato/Campione:Ord:Molgen
es-MXSpanish (Mexico)
Mutación de resistencia a la azitromicina del gen del rRNA 23S bacteriano:Presencia o umbral:Punto temporal:Aislado o espécimen:Ordinal:Genética molecular
es-ESSpanish (Spain)
Mutación del Gen 23S rRNA de resistencia a azitromicina:PrThr:Punto temporal:Muestra aislada:Ord:Genética molecular

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=89314-9