LOINC
Version 2.71

89373-5Hepatitis A virus genotype in Specimen by NAA with probe detectionActive

Part Descriptions

LP16708-7   Hepatitis A virus
Hepatitis A virus (Hep A or HAV) is an RNA virus that causes an acute infectious disease of the liver and is usually spread by the fecal-oral route. It is transmitted by ingestion of contaminated food or water or through direct contact with an infectious person. In developing countries, and in regions with poor hygiene standards, the incidence of infection with this virus is high. HAV infection produces a self-limited disease that usually does not result in chronic infection or chronic liver disease. Overall occurrence acute liver failure from Hepatitis A is rare (approx. 0.5%). The risk for symptomatic infection is directly related to age, with >80% of adults having symptoms compatible with acute viral hepatitis and the majority of children having either asymptomatic or unrecognized infection. Antibody produced in response to HAV infection persists for life and confers protection against reinfection. The disease can be prevented by vaccination, and hepatitis A vaccine has been proven effective in controlling outbreaks worldwide.

Although HAV is excreted in the feces towards the end of the incubation period, specific diagnosis is made by the detection of HAV-specific IgM antibodies in the blood. IgM antibody is only present in the blood following an acute hepatitis A infection. It is detectable from one to two weeks after the initial infection and persists for up to 14 weeks. The presence of IgG antibody in the blood means that the acute stage of the illness is past and the person is immune to further infection. IgG antibody to HAV is also found in the blood following vaccination and tests for immunity to the virus are based on the detection of this antibody. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Hepatitis A virus (Wikipedia)

LP16708-7   Hepatitis A virus
Hepatitis A virus (HAV) is a small, non-enveloped single-stranded RNA virus that belongs to the Picornaviridae family, genus Hepatovirus. HAV has six genotypes (I to VI) in which genotypes I to III are human isolates and IV to VI are only simian isolates. Genotypes I to III are subdivided into groups A and B. Genotype I is the most frequently reported. [PMID: 15914081] The clinical manifestations of HAV infection can vary significantly and range from asymptomatic infection, usually seen in young children, to fulminant hepatitis, which can result in death. HAV has a global distribution, and transmission primarily occurs by the fecal-oral route. The risk of HAV transmission through blood products is very low, but there have been some reports of transmission through plasma products, mainly coagulation factors. [PMID: 12186933] [PMID: 1318940] Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Regenstrief LOINC, Hepatitis A virus (Wikipedia)

Fully-Specified Name

Component
Hepatitis A virus genotype
Property
Type
Time
Pt
System
XXX
Scale
Nom
Method
Probe.amp.tar

Additional Names

Short Name
HAV Gentyp Spec NAA+probe
Display Name
HAV genotype NAA+probe Nom (Specimen)
Consumer Name Alpha
Hepatitis A virus (HAV) genotype, Specimen

Example Answer List LL4992-5

Source: Association of Public Health Laboratories

Answer Code Score Answer ID
Hepatitis A virus genotype I LA28917-5
Hepatitis A virus genotype II LA28918-3
Hepatitis A virus genotype III LA28919-1
Hepatitis A virus genotype IV LA28920-9
Hepatitis A virus genotype V LA28921-7
Hepatitis A virus subgenotype IA LA28923-3
Hepatitis A virus subgenotype IB LA28924-1
Hepatitis A virus subgenotype IIA LA28925-8
Hepatitis A virus subgenotype IIB LA28926-6
Hepatitis A virus subgenotype IIIA LA28927-4
Hepatitis A virus subgenotype IIIB LA28928-2
Not tested LA13538-6
Unable to complete sequencing LA28929-0

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.64
Last Updated
Version 2.69
Order vs. Observation
Both

Member of these Groups

LG32762-3 Hepatitis A virus

Language Variants Get Info

zh-CNChinese (China)
甲型肝炎病毒 基因型:类型:时间点:XXX:名义型:探针法.基因扩增.靶向
nl-NLDutch (Netherlands)
Hepatitis A-virus genotype:type:moment:XXX:nominaal:moleculaire techniek (PCR)
fr-BEFrench (Belgium)
Virus de l'hépatite A Génotype:Type:Temps ponctuel:XXX:Nominal:Sonde avec amplification de la cible
fr-CAFrench (Canada)
Virus de l'hépatite A , Génotype:Type:Temps ponctuel:XXX:Nominal:Sonde avec amplification de la cible
fr-FRFrench (France)
Hépatite A virus génotype:Type:Ponctuel:Milieux divers:Résultat nominal:PCR amplification de cible
de-DEGerman (Germany)
Hepatitis-A-Virus Genotyp:Typ:Pkt:XXX:Nom:Probe.amp.tar
el-GRGreek (Greece)
Ιός Ηπατίτιδας Α γονότυπος:Τύπος:Χρονική στιγμή:ΧΧΧ:Ονομαστική:Ανιχνευτής με ενίσχυση στόχου
it-ITItalian (Italy)
Epatite A, virus , genotipo:Tipo:Pt:XXX:Nom:Sonda.amp.tar
ru-RURussian (Russian Federation)
Гепатита А вирус генотип:Тип:ТчкВрм:XXX:Ном:Проба.усил.миш
es-ESSpanish (Spain)
Virus de la Hepatitis A Genotipo:Tipo:Punto temporal:XXX:Nom:Sonda con amplificación dirigida
tr-TRTurkish (Turkey)
Hepatit A virüsü genotip:Tip:Zmlı:XXX:Snf:Prob.amf.hdf

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=89373-5