LOINC
Version 2.72

89501-1Smith extractable nuclear Ab+Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Line blotActive

Term Description

This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Manufacturers call this method by different names, including immunoblot, line blot, and line immunoassay. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method for this term is Line blot.
Source: Regenstrief LOINC

Part Descriptions

LP18538-6   Smith extractable nuclear Ab+Ribonucleoprotein extractable nuclear
The presence of Smith antibody is specific for systemic lupus erythematosus (SLE), but occurs only in 30-35% of patients with SLE. The Smith and related nuclear ribonucleoproteins are targets for the autoantibodies developed by patients with SLE. Information from ARUP Laboratories (2007 10 15) and Jacobs and DeMott Laboratory Test Handbook, 5th edition, DS Jacobs, WR DeMott and DK Oxley, 2001. Source: Regenstrief Institute

LP18538-6   Smith extractable nuclear Ab+Ribonucleoprotein extractable nuclear
Antibodies to ribonucleoprotein(RNP) are eleveated in patients with Systemic lupus erythematosus (SLE) and other connective tissue disorders. Source: Regenstrief LOINC

Fully-Specified Name

Component
Smith extractable nuclear Ab+Ribonucleoprotein extractable nuclear Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
Line blot

Additional Names

Short Name
ENA SM+RNP Ab Ser Ql Line blot
Display Name
Smith extractable nuclear Ab+Ribonucleoprotein extractable nuclear Ab Line blot Ql (S)
Consumer Name Alpha
Smith extractable nuclear Ab+Ribonucleoprotein extractable nuclear antibody, Blood

Example Answer List LL744-4

Source: Regenstrief Institute

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.64
Last Updated
Version 2.64
Order vs. Observation
Both

Member of these Groups

LG9937-6 Smith extractable nuclear Ab+Ribonucleoprotein extractable nuclear Ab|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (China)
Smith 可提取性核抗体+核糖核蛋白可提取性核 抗体:存在情况或阈值:时间点:血清:序数型:线点印迹法
nl-NLDutch (Netherlands)
Smith extraheerbare nucleaire As + ribonucleoproteïne extraheerbare nucleaire As:aanwezigheid:moment:serum:ordinaal:lijnblot
fr-CAFrench (Canada)
Ac anti-nucléaire soluble Smith+Ribonucléoprotéine nucléaire soluble , Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Immunoessai sur bandelette
fr-FRFrench (France)
Sm+RNP anticorps:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Blot en ligne
it-ITItalian (Italy)
Smith, Ab nucleari estraibili+Nucleari estraibili ribonucleoproteina Ab:PrThr:Pt:Siero:Ord:Line blot
es-MXSpanish (Mexico)
Ab nuclear extraíble de Smith + Ab nuclear extraíble de ribonucleoproteína:Presencia o umbral:Punto temporal:Suero:Ordinal:Mancha de línea
es-ESSpanish (Spain)
Antigeno nuclear extraible Smith+Ribonucleoproteína nuclear extraible Anticuerpos:PrThr:Punto temporal:Suero:Ord:Line blot

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=89501-1