LOINC
Version 2.72

89504-5Ribosomal Ab [Presence] in Serum by Line blotActive

Term Description

This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Manufacturers call this method by different names, including immunoblot, line blot, and line immunoassay. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method for this term is Line blot.
Source: Regenstrief LOINC

Part Descriptions

LP18386-0   Ribosomal
A ribosome is an organelle in cells that assembles proteins. Ribosomes are composed of ribosomal RNA and ribosomal proteins (known as a Ribonucleoprotein or RNP). It translates Messenger RNA (mRNA) into a polypeptide chain (e.g., a protein). It can be thought of as a factory that builds a protein from a set of genetic instructions. Ribosomes can float freely in the cytoplasm (the internal fluid of the cell) or bind to the endoplasmic reticulum, or to the nuclear envelope. Since ribosomes are ribozymes, it is thought that they might be remnants of the RNA world. Ribosomes were first observed in the mid-1950s by cell biologist George Palade in the electron microscope as dense particles or granules for which he would win the Nobel Prize. The term ribosome was proposed by scientist Richard B. Roberts in 1958: During the course of the symposium a semantic difficulty became apparent. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Ribosomal (Wikipedia)

LP18386-0   Ribosomal
There are several ribosomal antigens. P (phospho) protein (P0, P1 & P2) is the most common. Other ribosomal antigens are L12 protein, L5/5s, S10, Ja, L7 and rRNA (ribosomal ribonucleoprotein) Source: Regenstrief Institute

Fully-Specified Name

Component
Ribosomal Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
Line blot

Additional Names

Short Name
Ribosomal Ab Ser Ql Line blot
Display Name
Ribosomal Ab Line blot Ql (S)
Consumer Name Alpha
Ribosomal antibody, Blood

Example Answer List LL744-4

Source: Regenstrief Institute

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.64
Last Updated
Version 2.64
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
88883-4 Connective tissue autoimmune Ab panel - Serum

Member of these Groups

LG9626-5 Ribosomal Ab|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (China)
核糖体 抗体:存在情况或阈值:时间点:血清:序数型:线点印迹法
nl-NLDutch (Netherlands)
ribosomaal As:aanwezigheid:moment:serum:ordinaal:lijnblot
fr-CAFrench (Canada)
Ribosomal , Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Immunoessai sur bandelette
fr-FRFrench (France)
Ribosomes anticorps:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Blot en ligne
it-ITItalian (Italy)
Ribosomiale Ab:PrThr:Pt:Siero:Ord:Line blot
es-MXSpanish (Mexico)
Ab ribosomal:Presencia o umbral:Punto temporal:Suero:Ordinal:Mancha de línea
es-ESSpanish (Spain)
Ribosomal Anticuerpos:PrThr:Punto temporal:Suero:Ord:Line blot

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=89504-5