LOINC
Version 2.72

89505-2Proteinase 3 Ab [Presence] in Serum by Line blotActive

Term Description

This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Manufacturers call this method by different names, including immunoblot, line blot, and line immunoassay. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method for this term is Line blot.
Source: Regenstrief LOINC

Part Description

LP17259-0   Proteinase 3
Proteinase 3 (PR3) is an enzyme contained in white blood cell neutrophils. It contributes to the breakdown of microbial proteins into polypeptides or amino acids (proteolysis). Antibodies to Proteinase 3 are a subgroup of anti-neutrophil cytoplasmic antibodies that can cause the disease granulomatosis with polyangitis that affects primarily the kidneys and the lungs. [PMID:21079042] Source: Regenstrief LOINC

Fully-Specified Name

Component
Proteinase 3 Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
Line blot

Additional Names

Short Name
Proteinase3 Ab Ser Ql Line blot
Display Name
Proteinase 3 Ab Line blot Ql (S)
Consumer Name Alpha
Proteinase 3 antibody, Blood

Example Answer List LL744-4

Source: Regenstrief Institute

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.64
Last Updated
Version 2.64
Order vs. Observation
Both

Member of these Groups

LG26752-2 Proteinase 3 Ab|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (China)
蛋白酶 3 抗体:存在情况或阈值:时间点:血清:序数型:线点印迹法
nl-NLDutch (Netherlands)
proteïnase 3 As:aanwezigheid:moment:serum:ordinaal:lijnblot
fr-CAFrench (Canada)
Protéinase 3 , Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Immunoessai sur bandelette
fr-FRFrench (France)
Protéinase 3 anticorps:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Blot en ligne
it-ITItalian (Italy)
Proteinasi 3 Ab:PrThr:Pt:Siero:Ord:Line blot
pl-PLPolish (Poland)
Proteinaza 3 przeciwciało:obecność lub wartość progowa:Punkt w czasie:Surowica:Porządkowy:Line blot
es-MXSpanish (Mexico)
Proteinasa 3 Ab:Presencia o umbral:Punto temporal:Suero:Ordinal:Mancha de línea
es-ESSpanish (Spain)
Proteinasa 3 Anticuerpos:PrThr:Punto temporal:Suero:Ord:Line blot

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=89505-2