89509-4Ganglioside GT1a IgG+IgM Ab [Presence] in Serum by Line blotActive
Term Description
This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Manufacturers call this method by different names, including immunoblot, line blot, and line immunoassay. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method for this term is Line blot.
Source: Regenstrief LOINC
Part Descriptions
LP99628-7 Ganglioside GT1a
Ganglioside GT1a is a central nervous system ganglioside that is present in several cranial nerves, including oculomotor, glossopharyngeal and vagal nerves. Anti-GT1a autoantibodies are found in patients with Guillain-Barre syndrome and frequently occur with anti-GQ1b antibodies. [PMID:12023422]
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Source: Regenstrief LOINC, PMID: 12023422
LP222219-0 Ganglioside
A ganglioside molecule consists of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acid residues linked to the sugar chain. Molecules with one sialic acid residue are called monosialogangliosides (GM), those with two are called disialogangliosides (GD), and those with three are trisialogangliosides (GT). Gangliosides without any sialic acid residues are called asialogangliosides, while those that do not have a ceramide N-acyl group are called lysogangliosides. The number that typically is included at the end of the name indicates the order in which the molecule was discovered. For example, GM2 is a ganglioside with one sialic acid residue that was the second GM to be identified.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Ganglioside GT1a Ab.IgG+IgM
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- Line blot
Additional Names
- Short Name
- GT1a Gangl IgG+IgM Ser Ql Line blot
- Display Name
- Ganglioside GT1a IgG+IgM Line blot Ql (S)
- Consumer Name Alpha
- Ganglioside GT1a IgG+IgM, Blood
Example Answer List LL744-4
Source: Regenstrief Institute
Answer | Code | Score | Answer ID |
---|---|---|---|
Detected | LA11882-0 | ||
Not detected | LA11883-8 |
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.64
- Last Updated
- Version 2.64
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
82455-7 | Ganglioside Ab panel - Serum |
Member of these Groups
LG26355-4 | Ganglioside GT1a Ab.IgG+IgM| |
Language Variants Get Info
- zh-CNChinese (China)
- 神经节苷脂 GT1a 抗体.IgG+IgM:
存在情况或阈值: 时间点: 血清: 序数型: 线点印迹法 - nl-NLDutch (Netherlands)
- ganglioside GT1a As.IgG + IgM:
aanwezigheid: moment: serum: ordinaal: lijnblot - fr-CAFrench (Canada)
- Ganglioside GT1a , IgG+IgM:
Présence-Seuil: Temps ponctuel: Sérum: Ordinal: Immunoessai sur bandelette - fr-FRFrench (France)
- Ganglioside GT1a anticorps IgG+IgM:
Présence/Seuil: Ponctuel: Sérum: Qualitatif: Blot en ligne - it-ITItalian (Italy)
- Ganglioside GT1a Ab.IgG+IgM:
PrThr: Pt: Siero: Ord: Line blot - es-MXSpanish (Mexico)
- Gangliósido GT1a Ab.IgG + IgM:
Presencia o umbral: Punto temporal: Suero: Ordinal: Mancha de línea - es-ESSpanish (Spain)
- Gangliosido GT1a IgG+IgM:
PrThr: Punto temporal: Suero: Ord: Line blot
LOINC FHIR® API Example - CodeSystem Request Get Info
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=89509-4
LOINC Copyright
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