LOINC
Version 2.72

89535-9Ribonucleoprotein extractable nuclear Ab [Presence] in Cerebral spinal fluid by Line blotActive

Term Description

This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Manufacturers call this method by different names, including immunoblot, line blot, and line immunoassay. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method for this term is Line blot.
Source: Regenstrief LOINC

Part Descriptions

LP14317-9   Ribonucleoprotein extractable nuclear
Ribonucleoprotein antibody (anti-RNP) is an antinuclear autoantibody (ANA) that binds to the U1-ribonucleoprotein of the ribonucleoprotein multi-enzyme complex. Anti-RNP belongs to the extractable nuclear antigen (ENA) subset of ANA. The anti-RNP binds with the U1-ribonucleoprotein, which is part of the ribonucleoprotein multi-enzyme complex. Anti-RNP-70 is a 70 kDa U1-RNP protein that provides the highest diagnostic sensitivity for MCTD. Some patients with autoimmune diseases, including systemic lupus erythematosus (SLE) and systemic sclerosis, can also produce anti-RNP antibodies.[http://autoimmunityblog.com/autoantibodies/from-g-to-p/ribonucleoprotein-antibodies-anti-rnp/] Source: Regenstrief LOINC

LP39569-6   Ribonucleoprotein extractable nuclear Ab
Antibodies to ribonucleoprotein(RNP) are eleveated in patients with Systemic lupus erythematosus (SLE) and other connective tissue disorders. Source: Regenstrief LOINC

Fully-Specified Name

Component
Ribonucleoprotein extractable nuclear Ab
Property
PrThr
Time
Pt
System
CSF
Scale
Ord
Method
Line blot

Additional Names

Short Name
ENA RNP Ab CSF Ql Line blot
Display Name
Ribonucleoprotein extractable nuclear Ab Line blot Ql (CSF)
Consumer Name Alpha
Ribonucleoprotein extractable nuclear antibody, Spinal fluid

Example Answer List LL744-4

Source: Regenstrief Institute

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.64
Last Updated
Version 2.64
Order vs. Observation
Both

Member of these Groups

LG26757-1 Ribonucleoprotein extractable nuclear Ab|PrThr|Pt|CSF

Language Variants Get Info

zh-CNChinese (China)
核糖核酸蛋白可提取性核 抗体:存在情况或阈值:时间点:脑脊液:序数型:线点印迹法
nl-NLDutch (Netherlands)
ribonucleoproteïne extraheerbare nucleaire As:aanwezigheid:moment:liquor cerebrospinalis:ordinaal:lijnblot
fr-CAFrench (Canada)
Ribonucléoprotéine nucléaire soluble , Ac:Présence-Seuil:Temps ponctuel:LCR:Ordinal:Immunoessai sur bandelette
fr-FRFrench (France)
RNP anticorps:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:Blot en ligne
it-ITItalian (Italy)
Ribonucleoproteina nucleare estraibile Ab:PrThr:Pt:LCS:Ord:Line blot
es-MXSpanish (Mexico)
Ab nuclear extraíble con ribonucleoproteína:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Mancha de línea
es-ESSpanish (Spain)
Ribonucleoproteína nuclear extraible Anticuerpos:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:Line blot

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=89535-9