LOINC
Version 2.72

89589-6Varicella zoster virus Ag [Presence] in Cerebral spinal fluid by ImmunofluorescenceActive

Part Description

LP14853-3   Varicella zoster virus
Varicella zoster virus (VZV) is a double-stranded alphaherpesvirus that causes seasonal outbreaks of chickenpox and shingles in non-immunized populations. VZV is highly infectious and is transmitted by contact with the ruptured fluid filled blisters and respiratory secretions of infected individuals. Immunity post infection is usually lifelong though the latent virus inhabits the sensory nerve ganglia where it can reactivate causing shingles when immunity declines with aging.[http://jvi.asm.org/content/88/24/13936.full] In the over fifty strains of VZV that have been sequenced it has been found that a single nucleotide polymorphism occurs about every 100 bases. The patterns of polymorphisms in VZV correlate with different geographical regions of infection and is the basis for the classification of viral clades.[https://grose.lab.uiowa.edu/vzv-genomes-and-evolution] Breuer proposed the nomenclature for the VZV clades as 1-5 with the suspected clades VI and VII to be confirmed later. The geographical regions associated with the seven clades are as follows:
Clades 1 and 3-represent the dominant clades of the circulating VZV in Europe and the Americas
Clades 4 and 5-found in Africa
Clade VI found in France, Italy
Clade VII exclusively isolated in the US
Clade 2-Asia from Korea, Japan, China not found in India, Nepal and Bangladesh where clades 4 and 5 were dominant
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054591/ Source: Regenstrief LOINC

Fully-Specified Name

Component
Varicella zoster virus Ag
Property
PrThr
Time
Pt
System
CSF
Scale
Ord
Method
IF

Additional Names

Short Name
VZV Ag CSF Ql IF
Display Name
VZV Ag IF Ql (CSF)
Consumer Name Alpha
Varicella zoster virus (VZV; Chickenpox) antigen, Spinal fluid

Example Answer List LL1937-3

Source: 3M Health Information Systems

Answer Code Score Answer ID
Present Copyright http://snomed.info/sct ID:52101004 Present (qualifier value) LA9633-4
Absent Copyright http://snomed.info/sct ID:2667000 Absent (qualifier value) LA9634-2

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.64
Last Updated
Version 2.64
Order vs. Observation
Both

Member of these Groups

LG32750-8 Varicella zoster virus

Language Variants Get Info

zh-CNChinese (China)
水痘带状疱疹病毒 抗原:存在情况或阈值:时间点:脑脊液:序数型:免疫荧光法
nl-NLDutch (Netherlands)
varicella-zostervirus Ag:aanwezigheid:moment:liquor cerebrospinalis:ordinaal:immunofluorescentie
et-EEEstonian (Estonia)
Tuulerõugeviirus antigeen:PrThr:Pt:CSF:Ord:IF
fr-BEFrench (Belgium)
Virus varicelle-zona Ag:PrThr:Temps ponctuel:LCR:Ordinal:Immunofluorescence
fr-CAFrench (Canada)
Virus varicelle-zona , Ag:Présence-Seuil:Temps ponctuel:LCR:Ordinal:Immunofluorescence
fr-FRFrench (France)
Varicelle zona virus Ag:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:Immunofluorescence
it-ITItalian (Italy)
Varicella zoster, virus , Ag:PrThr:Pt:LCS:Ord:IF
ru-RURussian (Russian Federation)
Varicella zoster вирус Аг:PrThr:ТчкВрм:ЦСЖ:Пор:ИФ
es-MXSpanish (Mexico)
Virus de la varicela zóster Ag:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Inmunofluorescencia (IF)
es-ESSpanish (Spain)
Virus Varicella zoster Antígeno:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:Inmunofluorescencia (IF)
tr-TRTurkish (Turkey)
Varicella zoster virüsü Ag:MevcEşik:Zmlı:BOS:Srl:IF

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=89589-6