LOINC
Version 2.67

90248-6Myelin oligodendrocyte glycoprotein IgG1 Ab [Presence] in Serum or Plasma by Flow cytometry (FC)Active

Part Description

LP268267-4   Myelin oligodendrocyte glycoprotein Ab.IgG1
Myelin oligodendrocyte glycoprotein (MOG) is a protein made up of two polypeptides with molecular masses of 26 and 28 kilodaltons, respectively. MOG is located on the surface of myelin and oligodendrocyte cytoplasmic membranes and binds to the monoclonal antibody 8-18C5. [PMID: 1373175] MOG is a probable autoantigen target associated with multiple sclerosis (MS) and other demyelinating diseases (DD) of the central nervous system. [PMID: 1373175] That being said, there is variation in the level of MOG antibody found in patients with MS and DD with inconsistencies between MOG antibody measurements using western blot and ELISA test methods, making it a questionable biomarker for DD. [PMID: 17294606] MOG IgG1 is the most prevalent isotype of IgG in patients with DD. [PMID: 29063242] Source: Regenstrief LOINC

Fully-Specified Name

Component
Myelin oligodendrocyte glycoprotein Ab.IgG1
Property
PrThr
Time
Pt
System
Ser/Plas
Scale
Ord
Method
Flow cytometry

Additional Names

Short Name
MOG IgG1 SerPl Ql FC
Display Name
Myelin oligodendrocyte glycoprotein IgG1 Ab FC Ql

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.65
Last Updated
Version 2.65
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Language Variants Get Info

zh-CNChinese (CHINA)
髓鞘少突胶质细胞糖蛋白 抗体.IgG1:存在情况或阈值:时间点:血清/血浆:序数型:流式细胞测量术
nl-NLDutch (NETHERLANDS)
myeline-oligodendrocyt-glycoproteïne As.IgG1:aanwezigheid:moment:serum of plasma:ordinaal:flowcytometrie
it-ITItalian (ITALY)
Glicoproteina oligodendrocita mielinica , Ab.IgG1:PrThr:Pt:Siero/Plasma:Ord:Citometria a flusso
es-ESSpanish (SPAIN)
Mielina de oligodendrocitos glicoproteína Inmunoglobulina G1:PrThr:Punto temporal:Suero o Plasma:Ord:Citometria de flujo (FC)

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