LOINC
Version 2.73

90846-7PCA-Tr Ab [Titer] in Cerebral spinal fluid by Cell binding immunofluorescent assayActive

Part Descriptions

LP31709-6   Purkinje cell cytoplasmic type Tr
Purkinje cell cytoplasmic-Tr (PCA-Tr) antibodies are associated with Hodgkin's lymphoma. The clinical presentation that corresponds with PCA-Tr antibodies includes paraneoplastic cerebellar degeneration (PCD) and limbic encephalopathy (LE).[PMID:22412264] PCD and LE are types of paraneoplastic neurological syndrome (PNS), an autoimmune disorder that is manifested by progressive neurological syndromes of any combination of the central, peripheral and autonomic nervous systems. The antibodies that attack the neural tissue develop in response to tumor cells. The neurological symptoms include encephalitis, autonomic failure, peripheral neuropathy, cerebellar ataxia, visual complaints and more. The neoplasm may or may not be detectable using conventional imaging modalities. Since PNS can be associated with multiple antibodies, testing usually includes a panel of PNS antibodies. In addition, the different PNS antibodies are associated with certain cancers so the antibody pattern can assist in identifying the specific tumor if it was previously undiagnosed.[PMID:22412264] Source: Regenstrief LOINC, Cytoplasmic

LP269367-1   CBA IFA
In cell binding assays or cell-based assays (CBA) also known as cell-based immunoassays, the DNA coding for a particular antigen is transfected into cultured cells, which are then used directly as substrate for antibody detection by immunofluorescence. The advantage of CBA IFA over conventional immunoassays is that purification and stability of the antigen is not required and they provide an in vivo substrate. Source: Regenstrief LOINC

Fully-Specified Name

Component
Purkinje cell cytoplasmic type Tr Ab
Property
Titr
Time
Pt
System
CSF
Scale
Qn
Method
CBA IFA

Additional Names

Short Name
PCA-Tr Ab Titr CSF CBA IFA
Display Name
PCA-Tr Ab Cell binding immunofluorescent assay (CSF) [Titer]
Consumer Name Alpha
PCA-Tr antibody, Spinal fluid

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.65
Last Updated
Version 2.69
Order vs. Observation
Both

Member of these Groups

LG20854-2 Purkinje cell cytoplasmic type Tr Ab|Titr|Pt|CSF

Language Variants Get Info

zh-CNChinese (China)
浦肯雅细胞胞浆 Tr 型 抗体:滴定度:时间点:脑脊液:定量型:CBA IFA
fr-FRFrench (France)
Tr anticorps:Titre:Ponctuel:Liquide céphalorachidien:Numérique:Immunofluorescence CBA
it-ITItalian (Italy)
Cellule di Purkinje tipo Tr Ab:Titr:Pt:LCS:Qn:CBA IFA
es-MXSpanish (Mexico)
Citoplasma de células de Purkinje tipo Tr Ab:Título:Punto temporal:Fluído espinal cerebral:Cuantitativo:Ensayo inmunofluorescente de unión a células
es-ESSpanish (Spain)
Células de Purkinje tipo Tr Anticuerpos:Titulo / Factor de dilución:Punto temporal:Líquido Cefalorraquideo:Qn:CBA IFA (inmunofluorescencia indirecta de estudio basqado en células)

Example Units

Unit Source
{titer} Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=90846-7