91774-0Varicella zoster virus Ag [Presence] in Lower respiratory specimen by ImmunofluorescenceActive
Part Description
LP14853-3 Varicella zoster virus
Varicella zoster virus (VZV) is a double-stranded alphaherpesvirus that causes seasonal outbreaks of chickenpox and shingles in non-immunized populations. VZV is highly infectious and is transmitted by contact with the ruptured fluid filled blisters and respiratory secretions of infected individuals. Immunity post infection is usually lifelong though the latent virus inhabits the sensory nerve ganglia where it can reactivate causing shingles when immunity declines with aging.[http://jvi.asm.org/content/88/24/13936.full] In the over fifty strains of VZV that have been sequenced it has been found that a single nucleotide polymorphism occurs about every 100 bases. The patterns of polymorphisms in VZV correlate with different geographical regions of infection and is the basis for the classification of viral clades.[https://grose.lab.uiowa.edu/vzv-genomes-and-evolution] Breuer proposed the nomenclature for the VZV clades as 1-5 with the suspected clades VI and VII to be confirmed later. The geographical regions associated with the seven clades are as follows:
Clades 1 and 3-represent the dominant clades of the circulating VZV in Europe and the Americas
Clades 4 and 5-found in Africa
Clade VI found in France, Italy
Clade VII exclusively isolated in the US
Clade 2-Asia from Korea, Japan, China not found in India, Nepal and Bangladesh where clades 4 and 5 were dominant
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054591/
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Varicella zoster virus Ag
- Property
- PrThr
- Time
- Pt
- System
- Respiratory.lower
- Scale
- Ord
- Method
- IF
Additional Names
- Short Name
- VZV Ag Lower resp Ql IF
- Display Name
- VZV Ag IF Ql (Lower resp)
- Consumer Name Alpha
- Varicella zoster virus (VZV; Chickenpox) antigen, Lower respiratory
Example Answer List LL744-4
Source: Regenstrief Institute
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Detected | LA11882-0 | ||
| Not detected | LA11883-8 |
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.66
- Last Updated
- Version 2.66
- Order vs. Observation
- Both
Member of these Groups
| LG32750-8 | Varicella zoster virus |
Language Variants Get Info
- zh-CNChinese (China)
- 水痘带状疱疹病毒 抗原:
存在情况或阈值: 时间点: 呼吸道.下: 序数型: 免疫荧光法 - nl-NLDutch (Netherlands)
- varicella-zostervirus Ag:
aanwezigheid: moment: onderste luchtwegen: ordinaal: immunofluorescentie - fr-CAFrench (Canada)
- Virus varicelle-zona , Ag:
Présence-Seuil: Temps ponctuel: Système respiratoire.inférieur: Ordinal: Immunofluorescence - fr-FRFrench (France)
- Varicelle zona virus Ag:
Présence/Seuil: Ponctuel: Voies respiratoires inférieures: Qualitatif: Immunofluorescence - it-ITItalian (Italy)
- Varicella zoster, virus , Ag:
PrThr: Pt: Sistema respiratorio.inferiore: Ord: IF - es-MXSpanish (Mexico)
- Virus de la varicela zóster Ag:
Presencia o umbral: Punto temporal: Muestra de vías respiratorias inferiores: Ordinal: Inmunofluorescencia (IF) - es-ESSpanish (Spain)
- Virus Varicella zoster Antígeno:
PrThr: Punto temporal: Tracto respiratorio inferior: Ord: Inmunofluorescencia (IF) - tr-TRTurkish (Turkey)
- Varicella zoster virüsü Ag:
MevcEşik: Zmlı: Respiratuvar.alt: Srl: IF
LOINC FHIR® API Example - CodeSystem Request Get Info
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=91774-0
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