LOINC
Version 2.72

93385-3Salmonella sp DNA [Presence] by NAA with probe detection in Positive blood cultureActive

Part Description

LP16750-9   Salmonella sp
Salmonella are gram-negative, flagellated, facultative intracellular, anaerobic bacilli with O, H and Vi surface antigens. Once ingested, Salmonella survives the gastric acid barrier and penetrates the epithelial cells of the small and large intestines. The invasion of the epithelial cells stimulates the release of cytokines and a subsequent inflammatory response leading to diarrhea and possible ulceration of the mucosa.[NCBI Books:8435] Antibodies to Salmonella are the body's defense when the bacteria is outside of its host cell which occurs at the initial infection and when the bacillus moves from cell to cell. There is a 10 minute window of opportunity when the Salmonella bacillus leaves the macrophage to invade another. During that time, antibodies and complement work to eradicate the bacilli, but some of the extracellular bacilli will evade attack and enter another host cell. Studies have shown that vaccines play an important role in the fight against typhoid fever.[PMID:25566248] There are two species of Salmonella: S. enterica and S. bongori. These species can be further subclassified into subspecies and serovars.

Veterinary Medicine:
Salmonella infection is most often caused by the serovars Salmonella choleraesuis, and Salmonella typhimurium and less often by Salmonella derby. Infected pigs can be asymptomatic and become carriers of S. choleraesius. Typically, the bacteria survive in the mesenteric lymph nodes that drain into the intestines, and are not shed in the feces unless the pig is under stress. The carrier state lasts for weeks to months and is self-limiting. Severe infection with S. choleraesius can be serious starting out as septicemia and progressing to pneumonia and enteritis. The infection can spread to various tissues including to the central nervous system leading to meningitis and to the joints where it manifests as arthritis. Severe infections with S. choleraesius occurs at any age, but most often in pigs 12-14 weeks of age.[http://www.thepigsite.com/pighealth/article/357/salmonellosis/] Source: Regenstrief LOINC

Fully-Specified Name

Component
Salmonella sp DNA
Property
PrThr
Time
Pt
System
Bld.pos growth
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
Salmonella DNA Bld Pos Ql NAA+probe
Display Name
Salmonella sp DNA NAA+probe Ql (Pos bld culture)
Consumer Name Alpha
Salmonella sp, Infected blood

Example Answer List LL744-4

Source: Regenstrief Institute

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.67
Last Updated
Version 2.67
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
93407-5 Gram negative blood culture panel by NAA with probe detection in Positive blood culture

Language Variants Get Info

zh-CNChinese (China)
沙门菌属 DNA:存在情况或阈值:时间点:血液.生长阳性:序数型:探针法.基因扩增.靶向
nl-NLDutch (Netherlands)
Salmonella sp. DNA:aanwezigheid:moment:positieve bloedkweek:ordinaal:moleculaire techniek (PCR)
fr-FRFrench (France)
Salmonella ADN:Présence/Seuil:Ponctuel:Hémoculture positive:Qualitatif:PCR amplification de cible
it-ITItalian (Italy)
Salmonella sp DNA:PrThr:Pt:Emocolture positive:Ord:Sonda.amp.tar
ru-RURussian (Russian Federation)
Salmonella sp ДНК:PrThr:ТчкВрм:Кр.положит рост:Пор:Проба.усил.миш
es-MXSpanish (Mexico)
ADN de Salmonella sp:Presencia o umbral:Punto temporal:Hemocultivo positivo:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
es-ESSpanish (Spain)
Salmonella sp ADN:PrThr:Punto temporal:Sangre crecimiento positivo:Ord:Sonda con amplificación dirigida
tr-TRTurkish (Turkey)
Salmonella sp DNA:MevcEşik:Zmlı:Kan.poz büyüme:Srl:Prob.amf.hdf

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=93385-3