LOINC
Version 2.73

93424-0Glial fibrillary acidic protein alpha subunit IgG Ab [Presence] in Serum by Cell binding immunofluorescent assayActive

Part Descriptions

LP411550-9   Glial fibrillary acidic protein.alpha subunit Ab.IgG
Glial fibrillary acidic protein (GFAP) antibody is a biomarker for immune inflammation. GFAP IgG autoantibody binds to GFAPα, and is found in serum and cerebrospinal fluid (CSF) of indiviuals with GFAP astrocytopathy. GFAP antibodies are detectable by immunofluorescence (IF), cell-based assay (CBA) and western blot. GFAP astrocytopathy often overlaps with other autoimmune diseases, making diagnosis challenging due to the coexisting neural autoantibodies. [PMID:30568655] Source: Regenstrief LOINC

LP269367-1   CBA IFA
In cell binding assays or cell-based assays (CBA) also known as cell-based immunoassays, the DNA coding for a particular antigen is transfected into cultured cells, which are then used directly as substrate for antibody detection by immunofluorescence. The advantage of CBA IFA over conventional immunoassays is that purification and stability of the antigen is not required and they provide an in vivo substrate. Source: Regenstrief LOINC

Fully-Specified Name

Component
Glial fibrillary acidic protein.alpha subunit Ab.IgG
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
CBA IFA

Additional Names

Short Name
GFAP alpha IgG Ser Ql CBA IFA
Display Name
Glial fibrillary acidic protein alpha subunit IgG Cell binding immunofluorescent assay Ql (S)
Consumer Name Alpha
Glial fibrillary acidic protein alpha subunit IgG antibody, Blood

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.67
Last Updated
Version 2.69
Change Reason
Release 2.68: COMPONENT: Added "subunit" to Component name for consistency across terms.
Order vs. Observation
Both

Member of these Groups

LG51002-0 Glial fibrillary acidic protein.alpha subunit Ab.IgG|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (China)
神经胶质纤维酸性蛋白.alpha 亚单位 抗体.IgG:存在情况或阈值:时间点:血清:序数型:CBA IFA
fr-FRFrench (France)
GFAP alpha anticorps IgG:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunofluorescence CBA
it-ITItalian (Italy)
Proteina acida fibrillare gliale.alfa Ab.IgG:PrThr:Pt:Siero:Ord:CBA IFA
es-MXSpanish (Mexico)
Proteína ácida fibrilar glial subunidad alfa IgG:Presencia o umbral:Punto temporal:Suero:Ordinal:Ensayo inmunofluorescente de unión a células
es-ESSpanish (Spain)
Subunidad alfa de la proteína ácida fibrilar glial IgG:PrThr:Punto temporal:Suero:Ord:CBA IFA (inmunofluorescencia indirecta de estudio basqado en células)

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=93424-0