LOINC
Version 2.68

93502-3NMDAR subunit 1 IgG Ab [Presence] in Cerebral spinal fluid by Cell binding assay immunofluorescent assayActive

Part Description

LP229977-6   N-methyl-D-aspartate receptor subunit 1
N-methyl-D-aspartate receptor 1 (NMDAR1) is subunit of NMDA receptors and belongs to the glutamate receptor channel superfamily. It is encoded by the GRIN1 (Glutamate [NMDA] receptor subunit zeta-1) gene located on chromosome 9q34.3.[UniProt: Q05586] Glutamate receptors are highly permeable to calcium and important for nervous system functioning. NMDAR1 antibodies are detected in patients with paraneoplastic syndromes, autoimmune encephalopathies and related conditions. Identification of specific antineuronal autoantibodies may direct evaluation for underlying malignancy. Characterization of autoantibody specificity may allow syndromic classification and assist in diagnosis and management. Source: Regenstrief LOINC

Fully-Specified Name

Component
N-methyl-D-aspartate receptor subunit 1 Ab.IgG
Property
PrThr
Time
Pt
System
CSF
Scale
Ord
Method
CBA IFA

Additional Names

Short Name
NMDAR1 IgG CSF Ql CBA IFA
Display Name
NMDAR subunit 1 IgG Cell binding assay immunofluorescent assay Ql (CSF)

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.67
Last Updated
Version 2.67
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Panels

LOINC Long Common Name
94707-7 Dementia autoimmune Ab panel - Cerebral spinal fluid
94708-5 Encephalopathy autoimmune Ab panel - Cerebral spinal fluid
94709-3 Epilepsy autoimmune Ab panel - Cerebral spinal fluid
94712-7 Movement disorder autoimmune Ab panel - Cerebral spinal fluid

Language Variants Get Info

zh-CNChinese (CHINA)
N-甲基-D-天冬氨酸受体亚单位 1 抗体.IgG:存在情况或阈值:时间点:脑脊液:序数型:CBA IFA
it-ITItalian (ITALY)
N-metil-D-aspartato, subunità 1 recettore , Ab.IgG:PrThr:Pt:LCS:Ord:CBA IFA
es-ESSpanish (SPAIN)
Subunidad 1 del receptor de N-metil-D-aspartato (NMDAR-1) IgG:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:CBA IFA (inmunofluorescencia indirecta de estudio basqado en células)

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=93502-3