Version 2.73

94098-1Dense fine speckled 70 protein IgG Ab [Presence] in Serum or Plasma by ImmunoassayActive

Term Description

Detection of IgG antibodies against DFS70 (dense fine speckled 70 antigen) in serum or plasma to assist in the diagnosis of autoimmune diseases. The term was created for, but not limited in use to, the submitter's test kit, Euroimmun Anti-DFS70 ELISA (IgG), which calculates the ratio of the extinction value of the control or patient sample over the extinction value of the calibrator. A ratio of greater than or equal to 1.0 is considered positive. A negative serological result does not exclude the presence of disease.
Source: Regenstrief LOINC

Part Description

LP230331-3   Dense fine speckled 70 protein Ab.IgG
Antinuclear antibodies are essential to diagnose systemic autoimmune rheumatic diseases (SARDs) such as Lupus erythematosus and scleroderma. However, 20-30% of healthy people test positive for ANAs,half of which are dense fine speckled 70 protein (DFS70) antibodies. DFS70 antibodies have been found in patients with various chronic inflammatory diseases but no one disease in particular. It has been suggested that the best use for measuring DFS70 antibodies might be as a biomarker that excludes the diagnosis of SARD since DFS70 antibodies are more often found in patients without active SARD than with it. Antibody titers of DFS70 are highest in healthy young females and the titers decline as a person ages.( http://cli-online.com/featured-articles/anti-dfs70-antibodies-detection-and-significance/) Source: Regenstrief LOINC

Fully-Specified Name

Dense fine speckled 70 protein Ab.IgG

Additional Names

Short Name
DFS70 IgG SerPl Ql IA
Display Name
Dense fine speckled 70 protein IgG IA Ql
Consumer Name Alpha
Dense fine speckled 70 protein IgG antibody, Blood

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

First Released
Version 2.67
Last Updated
Version 2.67
Order vs. Observation

Member of these Groups

LG50952-7 Dense fine speckled 70 protein Ab.IgG|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (China)
致密细斑 70 蛋白 抗体.IgG:存在情况或阈值:时间点:血清/血浆:序数型:免疫测定法
nl-NLDutch (Netherlands)
dense fine speckled 70 protein As.IgG:aanwezigheid:moment:serum of plasma:ordinaal:immunoassay
fr-FRFrench (France)
DFS70 anticorps IgG:Présence/Seuil:Ponctuel:Sérum/Plasma:Qualitatif:Immunoanalyse
it-ITItalian (Italy)
Proteina 70 densa fine punteggiata Ab.IgG:PrThr:Pt:Siero/Plasma:Ord:IA
es-MXSpanish (Mexico)
Ab.IgG de proteína 70 moteada fina y densa:Presencia o umbral:Punto temporal:Suero o Plasma:Ordinal:Inmunoensayo
es-ESSpanish (Spain)
Proteína densa fina moteada 70 IgG:PrThr:Punto temporal:Suero o Plasma:Ord:IA

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