LOINC
Version 2.73

94285-4Contactin-associated protein 2 IgG Ab [Presence] in Serum by Cell binding immunofluorescent assayActive

Part Descriptions

LP230270-3   Contactin-associated protein 2
Contactin-associated protein 2 (CASPR2) is present in the axons of the granule neurons of the cerebellum and the juxtaparanodal region of myelinated axons. Increased titers of CASPR2 antibodies were first discovered in patients with Morvan's syndrome. Symptoms of Morvan's syndrome include neuromyotonia, insomnia, autonomic dysfunction and neuropathic pain. Though CASPR2 antibodies have been found in 10% of patients with idiopathic cerebellar ataxia, no specific disease has been attributed to patients with the rare occurrence of positive antibodies for CASPR2 with cerebellar involvement.[PMID:25846566] Source: Regenstrief LOINC

LP269367-1   CBA IFA
In cell binding assays or cell-based assays (CBA) also known as cell-based immunoassays, the DNA coding for a particular antigen is transfected into cultured cells, which are then used directly as substrate for antibody detection by immunofluorescence. The advantage of CBA IFA over conventional immunoassays is that purification and stability of the antigen is not required and they provide an in vivo substrate. Source: Regenstrief LOINC

Fully-Specified Name

Component
Contactin-associated protein 2 Ab.IgG
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
CBA IFA

Additional Names

Short Name
CASPR2 IgG Ser Ql CBA IFA
Display Name
Contactin-associated protein 2 IgG Cell binding immunofluorescent assay Ql (S)
Consumer Name Alpha
Contactin-associated protein 2 IgG antibody, Blood

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.68
Last Updated
Version 2.69
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
94695-4 Axonal autoimmune Ab panel - Serum or Plasma
94696-2 Dementia autoimmune Ab panel - Serum or Plasma
94697-0 Encephalopathy autoimmune Ab panel - Serum or Plasma
94698-8 Epilepsy autoimmune Ab panel - Serum or Plasma
94701-0 Movement disorder autoimmune Ab panel - Serum or Plasma

Member of these Groups

LG50958-4 Contactin-associated protein 2 Ab.IgG|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (China)
接触蛋白关联蛋白 2 抗体.IgG:存在情况或阈值:时间点:血清:序数型:CBA IFA
fr-FRFrench (France)
CASPR2 anticorps IgG:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunofluorescence CBA
it-ITItalian (Italy)
Proteina 2 Contactin-associata Ab.IgG:PrThr:Pt:Siero:Ord:CBA IFA
es-MXSpanish (Mexico)
Proteína 2 Ab.IgG asociada a contactina:Presencia o umbral:Punto temporal:Suero:Ordinal:Ensayo inmunofluorescente de unión a células
es-ESSpanish (Spain)
Proteína 2 asociada a contactina IgG:PrThr:Punto temporal:Suero:Ord:CBA IFA (inmunofluorescencia indirecta de estudio basqado en células)

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=94285-4