LOINC
Version 2.72

94290-4Saint Louis encephalitis virus neutralizing antibody [Presence] in Specimen by Neutralization testActive

Part Descriptions

LP14232-0   Saint Louis encephalitis virus
St. Louis Encephalitis is a disease caused by the mosquito borne St. Louis Encephalitis virus. St. Louis encephalitis virus is related to Japanese encephalitis virus. This disease mainly affects the United States. Occasional cases have been reported from Canada and Mexico. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, St. Louis enphalitis virus

LP6416-4   Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. [PMID:32170698] This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. [PMID:169804] Source: Regenstrief LOINC

LP207365-0   Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method. Source: Regenstrief LOINC

Fully-Specified Name

Component
Saint Louis encephalitis virus Ab.Neut
Property
PrThr
Time
Pt
System
XXX
Scale
Ord
Method
Neut

Additional Names

Short Name
SLEV NAb Spec Ql Nt
Display Name
SLEV neut ab Neut test Ql (Specimen)
Consumer Name Alpha
SLEV neutralizing antibody, Specimen

Example Answer List LL744-4

Source: Regenstrief Institute

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.68
Last Updated
Version 2.72
Change Reason
Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.;
Order vs. Observation
Both

Member of these Groups

LG32753-2 Saint Louis encephalitis virus

Language Variants Get Info

zh-CNChinese (China)
圣路易型脑炎病毒 抗体.中和:存在情况或阈值:时间点:XXX:序数型:中和试验
nl-NLDutch (Netherlands)
Saint Louis-encefalitisvirus As.neutraliserend:aanwezigheid:moment:XXX:ordinaal:neutralisatietest
fr-FRFrench (France)
Encéphalite de Saint-Louis virus Ac:Présence/Seuil:Ponctuel:Milieux divers:Qualitatif:Neutralisation
it-ITItalian (Italy)
Encefalite di Saint Louis, virus Ab.Neut:PrThr:Pt:XXX:Ord:Neut
es-MXSpanish (Mexico)
Virus de la encefalitis de Saint Louis Ab:Presencia o umbral:Punto temporal:XXX:Ordinal:Prueba de neutralización
es-ESSpanish (Spain)
Virus de la encefalitis de Saint Louis Anticuerpos antineutrófilos:PrThr:Punto temporal:XXX:Ord:Prueba de neutralización

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=94290-4