Version 2.77

Term Description

Quantitative measurement of Histoplasma capsulatum antigens in bronchoalveolar lavage (BAL) specimens by immunoassay methods for the diagnosis and monitoring of histoplasmosis. PMID: 28275076 Monitoring of histoplasmosis is performed to diagnose relapse and help determine when treatment can be stopped.
Source: Regenstrief LOINC

Part Description

LP16650-1   Histoplasma capsulatum
Histoplasmosis capsulatum is a dimorphic fungal pathogen with filamentous or yeast forms,depending on nutritional factors and temperature.The M antigen is a well-known glycoprotein used as a diagnostic antigen for acute histoplasmosis as it induces the first precipitins during disease. Monoclonal antibodies (mAbs) to the M antigen have been found to modify the pathogenesis of histoplasmosis.Given the shortcomings of current therapies, the administration of mAbs is being investigated. PMID: 22347215 The H band is less commonly seen than the M band and is indicative of chronic or severe acute infections with H capsulatum.

H. capsulatum is found in nature primarily as a saprophytic mold. The mold form is comprised of hyaline septate hyphae, which produce two different asexual reproduction structures, macroconidia and microconidia. The micronidia are believed to be responsible for disease propagation since their 2-6 µm size is well suited for disposition into the distal alveoli. Infection is typically acquired through inhalation of fungal propagules upon disturbances of contaminated soil or excreta. Environmental and genetic factors influence disease manifestations which can range from asymptomatic or mild influenza-like disease to a disseminated sepsis form. Manifestations depend on the magnitude of exposure, the host's immunological status and the virulence of the infective strain. Reactivation of latent infection can result in significant disease, particularly for immunosuppressed individuals. Despite the availability of potent antifungal drugs, nearly one in ten patients hospitalized with histoplasmosis dies. PMID: 17223625 Source: Regenstrief LOINC

Fully-Specified Name

Component
Histoplasma capsulatum Ag
Property
MCnc
Time
Pt
System
BAL
Scale
Qn
Method
IA

Additional Names

Short Name
H capsul Ag BAL IA-mCnc
Display Name
H. capsulatum Ag IA (BAL) [Mass/Vol]
Consumer Name Alpha Get Info
Histoplasma capsulatum antigen, Bronchoalveolar lavage specimen

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.68
Last Updated
Version 2.68
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Histoplasma capsulatum Antígeno:Concentración de masa:Punto temporal:Lavado broncoalveolar:Qn:IA
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Histoplasma capsulatum Ag:Concentración de masa:Punto temporal:Lavado broncoalveolar:Cuantitativo:Inmunoensayo
et-EE Estonian (Estonia) Histoplasma capsulatum antigeen:MCnc:Pt:BalF:Qn:IA
Synonyms: Juhuslik Kvantitatiivne
fr-FR French (France) Histoplasma capsulatum Ag:Masse/Volume:Ponctuel:Liquide bronchoalvéolaire:Numérique:Immunoanalyse
fr-BE French (Belgium) Histoplasma capsulatum Ag:Concentration de masse:Temps ponctuel:Lavage broncho-alvéolaire:Quantitatif:IA
Synonyms: Antigène
fr-CA French (Canada) Histoplasma capsulatum , Ag:Concentration de masse:Temps ponctuel:Lavage broncho-alvéolaire:Quantitatif:IA
it-IT Italian (Italy) Histoplasma capsulatum , Ag:MCnc:Pt:BAL:Qn:IA
Synonyms: Concentrazione di Massa Immunoassay Lavaggio Bronco Alveolare Microbiologia Punto nel tempo (episodio)
nl-NL Dutch (Netherlands) Histoplasma capsulatum Ag:massa/volume:moment:bronchoalveolaire wassing:kwantitatief:immunoassay
Synonyms: antigeen IA
ru-RU Russian (Russian Federation) Histoplasma capsulatum Аг:МассКонц:ТчкВрм:БАЛ:Колич:IA
Synonyms: Бронхоальвеолярный лаваж Количественный Массовая концентрация Точка во времени;Момент
tr-TR Turkish (Turkey) Histoplazma Kapsulatum Ag:KütlKons:Zmlı:BAL:Kant:İA
Synonyms: Antijen Bronkoalveoler lavaj İmmünölçüm, immünoassay
zh-CN Chinese (China) 荚膜组织胞浆菌 抗原:质量浓度:时间点:支气管肺泡灌洗液:定量型:免疫测定法
Synonyms: Ag 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 支气管肺泡洗液 时刻;随机;随意;瞬间 水平;浓度;质量浓度(单位体积) 皮疽组织胞浆菌 Ag 皮疽组织胞浆菌;美洲型组织胞浆菌;鼻疽性组织浆菌 皮疽组织胞浆菌抗原 组织胞浆菌属 组织胞浆菌病 美洲型组织胞浆菌 Ag 美洲型组织胞浆菌抗原 荚膜组织胞浆菌 Ag 鼻疽性组织浆菌 Ag 鼻疽性组织浆菌抗原

Example Units

Unit Source
ng/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=95073-3