95155-8
PRRSV ORF5 gene sequence homology to Prevacent in Isolate by Sequencing
Active
Term Description
Percent genomic homology between a new isolated PRRS virus strain and a PPRS vaccine strain (e.g. Lelystad, Fostera, IngelvacMLV, IngelvacATP, PrimePac and Prevacent) is based on the number of matching amino acids per total amino acids sequenced in the open reading frame 5 (ORF5) gene. The more homologous the ORF5 gene sequences, the more closely the variants are related. It is thought that sequence homology between isolates and vaccines will predict vaccine efficacy, however this is currently debated since little is known about the immune response to PRRS virus.
Source: Regenstrief LOINC
Part Description
LP150045-5 Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Porcine reproductive and respiratory syndrome virus ORF5 gene sequence homology to Prevacent
- Property
- NFr
- Time
- Pt
- System
- Isolate
- Scale
- Qn
- Method
- Sequencing
Additional Names
- Short Name
- PRRSV Prevacent Hmlgy Islt Seq-NFr
- Display Name
- PRRSV ORF5 gene sequence homology to Prevacent Sequencing (Isol)
- Consumer Name Alpha Get Info
- PRRSV ORF5 gene Sequence Homology to Prevacent
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.68
- Order vs. Observation
- Both
Formula (Readable)
(# of matching amino acids/total amino acids sequenced)*100 = % homology
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Homología de secuencia del gen ORF5 del virus del síndrome respiratorio y reproductivo porcino con Prevacent: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Homología de secuencia del gen ORF5 del virus del síndrome respiratorio y reproductivo porcino con Prevacent: |
it-IT | Italian (Italy) | Virus della sindrome riproduttiva e respiratoria del suino, sequenziamento del gene ORF5 a Prevacent: Synonyms: Frazione numerica Gene ORF5 virus PRRS Microbiologia Punto nel tempo (episodio) Sequenziamento del gene ORF5 a Prevacent virus PRRS Sequenziamento del gene ORF5 virus PRRS Virus PRRS |
nl-NL | Dutch (Netherlands) | 'porcine' reproductief en respiratoir syndroomvirus ORF5-gensequentie homologie met Prevacent: Synonyms: porcine voortplantings- en respiratoir syndroom virus van varken; |
zh-CN | Chinese (China) | 猪生殖与呼吸综合征病毒 ORF5 基因序列 Prevacent 同源物: Synonyms: Lelystad 病毒; |
Example Units
Unit | Source |
---|---|
% | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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