LOINC
Version 2.68

95410-7SARS-CoV-2 (COVID-19) neutralizing antibody [Titer] in Serum by pVNTActive

Term Description

Quantitative titer results for SARS Coronavirus 2 (SARS-CoV-2) virus neutralizing antibodies in serum by pVNT (pseudovirus neutralization test). Neutralizing antibody testing is performed to determine whether the antibodies produced after SARS-CoV-2 infection or in response to a vaccination are able to neutralize the virus and prevent infection or re-infection. Different methods can be used to determine the presence of neutralizing antibodies, including VNT (virus neutralization test) and pVNT, which are represented in LOINC as the Method "Neutralization" and "pVNT", respectively. The pVNT method for SARS-CoV-2 neutralizing antibody testing uses recombinant pseudoviruses that incorporate the S protein from SARS-CoV-2, whereas VNT uses SARS-CoV-2 virus from a clinical isolate or recombinant SARS-CoV-2 expressing reporter proteins.
Source: Regenstrief LOINC

Fully-Specified Name

Component
SARS coronavirus 2 Ab.neut
Property
Titr
Time
Pt
System
Ser
Scale
Qn
Method
pVNT

Additional Names

Short Name
SARS-CoV-2 NAb Titr Ser pVNT
Display Name
SARS-CoV-2 (COVID-19) neut ab pVNT (S) [Titer]

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.68
Last Updated
Version 2.68
Order vs. Observation
Observation

Reference Information

Type Source Reference
Webcontent Lab Tests Online®Copyright Copyright © 2001-2019 American Association for Clinical Chemistry Coronavirus (COVID-19) Testing

Member of these Groups

LG51018-6 SARSCoV2 antibody detection

Example Units

Unit Source
{titer} Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=95410-7