95644-1
Japanese encephalitis virus neutralizing antibody [Titer] in Specimen by Neutralization test
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Part Descriptions
LP17702-9 Japanese encephalitis virus
Japanese Encephalitis, previously known as Japanese B encephalitis to distinguish it from von Economo's A encephalitis) is a disease caused by the mosquito -borne Japanese Encephalitis Virus. Japanese Encephalitis Virus is a virus from the family Flaviviridae. Domestic pigs and wild birds are reservoirs of the virus; transmission to humans may cause severe symptoms. One of the most important vectors of this disease is the mosquito Culex tritaeniorhynchus. This disease is most prevalent in Southeast Asia and the Far East.
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Source: Wikipedia, Japanese encephalitis virus (Wikipedia)
LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method.
Source: Regenstrief LOINC
LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Japanese encephalitis virus Ab.Neut
- Property
- Titr
- Time
- Pt
- System
- XXX
- Scale
- SemiQn
- Method
- Neut
Additional Names
- Short Name
- JEV NAb Titr Spec Nt
- Display Name
- JEV neut ab Neut test (Specimen) [Titer]
- Consumer Name Alpha Get Info
- JEV neutralizing antibody, Specimen
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.69
- Last Updated
- Version 2.75
- Change Reason
- Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.;
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Virus de la encefalitis japonesa Anticuerpos antineutrófilos: Synonyms: Semicuantitativo |
es-MX | Spanish (Mexico) | Virus de la encefalitis japonesa Ab: |
fr-CA | French (Canada) | Virus de l'encéphalite Japonaise Ac.neut: |
fr-FR | French (France) | Encéphalite japonaise virus Ac neutralisant: |
it-IT | Italian (Italy) | Encefalite giapponese, virus Ab.Neut: Synonyms: anticorpo Microbiologia Punto nel tempo (episodio) Test di neutralizzazione Titolo Virus dell''encefalite giapponese |
nl-NL | Dutch (Netherlands) | Japanse encefalitis virus As.neutraliserend: Synonyms: antistof; |
pl-PL | Polish (Poland) | Wirus japońskiego zapalenia mózgu Ab.Neutralizujące: Synonyms: Przeciwciała do wirusa japońskiego zapalenia mózgu Przeciwciało neutralizujące do wirusa japońskiego zapalenia mózgu Wirus japońskiego zapalenia mózgu |
zh-CN | Chinese (China) | 日本脑炎病毒 抗体.中和: Synonyms: Ab; |
Example Units
Unit | Source |
---|---|
{titer} | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=95644-1
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright