95646-6
Ross River virus neutralizing antibody [Titer] in Specimen by Neutralization test
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Part Descriptions
LP14417-7 Ross river virus
Ross River virus (RRV) is a species in the genus Alphavirus, family Togaviridae. [https://talk.ictvonline.org/taxonomy/p/taxonomy-history?taxnode_id=201905103] RRV is a mosquito-borne virus that is common in Australia. Symptoms of RRV disease include fever, joint and muscle pain, and lethargy and may last 6 months or longer. Hosts include kangaroos, wallabies, and other marsupials, as well as sheep, birds, and horses. PMID: 32418511
Source: Regenstrief LOINC
LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method.
Source: Regenstrief LOINC
LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Ross River virus Ab.Neut
- Property
- Titr
- Time
- Pt
- System
- XXX
- Scale
- SemiQn
- Method
- Neut
Additional Names
- Short Name
- RRV NAb Titr Spec Nt
- Display Name
- Ross River virus neut ab Neut test (Specimen) [Titer]
- Consumer Name Alpha Get Info
- Ross River virus neutralizing antibody, Specimen
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.69
- Last Updated
- Version 2.75
- Change Reason
- Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.;
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Ross-River-Virus Ak.neutralisierend: Synonyms: RRV |
es-ES | Spanish (Spain) | Virus de Ross River Anticuerpos antineutrófilos: Synonyms: Semicuantitativo |
es-MX | Spanish (Mexico) | Virus del río Ross Ab: |
fr-FR | French (France) | Virus de la Ross River Ac neutralisant: |
fr-CA | French (Canada) | Virus de la rivière Ross Ac.neut: |
it-IT | Italian (Italy) | Fiume Ross, virus Ab.Neut: Synonyms: anticorpo Microbiologia Punto nel tempo (episodio) Test di neutralizzazione Titolo Virus del Fiume Ross |
nl-NL | Dutch (Netherlands) | Ross river-virus As.neutraliserend: Synonyms: antistof; |
pl-PL | Polish (Poland) | Wirus Rzeki Ross Ab.Neutralizujące: Synonyms: Przeciwciała do wirusa gorączki Rzeki Ross Przeciwciała neutralizujące do wirusa gorączki Rzeki Ross Wirus gorączki Rzeki Ross |
zh-CN | Chinese (China) | 罗斯河病毒 抗体.中和: Synonyms: Ab; |
Example Units
Unit | Source |
---|---|
{titer} | Example UCUM Units |
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- CodeSystem lookup
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