95648-2
Sindbis virus neutralizing antibody [Titer] in Specimen by Neutralization test
Active
Part Descriptions
LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method.
Source: Regenstrief LOINC
LP21131-5 Sindbis virus
The type species of ALPHAVIRUS normally transmitted to birds by CULEX mosquitoes in Egypt, South Africa, India, Malaya, the Philippines, and Australia. It may be associated with fever in humans. Serotypes (differing by less than 17% in nucleotide sequence) include Babanki, Kyzylagach, and Ockelbo viruses.
Source: National Library of Medicine, MeSH 2006
LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Sindbis virus Ab.Neut
- Property
- Titr
- Time
- Pt
- System
- XXX
- Scale
- SemiQn
- Method
- Neut
Additional Names
- Short Name
- SINV NAb Titr Spec Nt
- Display Name
- Sindbis virus neut ab Neut test (Specimen) [Titer]
- Consumer Name Alpha Get Info
- Sindbis virus neutralizing antibody, Specimen
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.69
- Last Updated
- Version 2.75
- Change Reason
- Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.;
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Virus Sindbis Anticuerpos antineutrófilos: Synonyms: Semicuantitativo |
es-MX | Spanish (Mexico) | Virus Sindbis Ab: |
fr-CA | French (Canada) | Virus Sindbis Ac.neut: |
fr-FR | French (France) | Sindbis virus Ac neutralisant: |
it-IT | Italian (Italy) | Sindbis virus Ab.Neut: Synonyms: anticorpo Microbiologia Punto nel tempo (episodio) SINV Test di neutralizzazione Titolo |
nl-NL | Dutch (Netherlands) | Sindbisvirus As.neutraliserend: Synonyms: antistof; |
pl-PL | Polish (Poland) | Wirus Sindbis Ab.Neutralizujące: Synonyms: Przeciwciała do wirusa Sindbis Przeciwciała neutralizujące do wirusa Sindbis |
zh-CN | Chinese (China) | 辛德毕斯病毒 抗体.中和: Synonyms: Ab; |
Example Units
Unit | Source |
---|---|
{titer} | Example UCUM Units |
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- CodeSystem lookup
- https:
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