95774-6
MSH6 gene deletion+duplication and full mutation analysis in Blood or Tissue by Molecular genetics method
Active
Part Description
LP34973-5 MSH6 gene
The MSH6 gene (mutS homolog 6) [HGNC Gene ID:7329] is located on chromosome 2p16. This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013] [NCBI Gene ID:2956]
Source: National Center for Biotechnology Information (NCBI) Gene
Fully-Specified Name
- Component
- MSH6 gene deletion+duplication & full mutation analysis
- Property
- Find
- Time
- Pt
- System
- Bld/Tiss
- Scale
- Doc
- Method
- Molgen
Additional Names
- Short Name
- MSH6 gene Del+Dup + Full Mut Anl Bld/T
- Display Name
- MSH6 gene del+dup and full mutation analysis Molgen Doc (Bld/Tiss)
- Consumer Name Alpha Get Info
- MSH6 gene variant analysis, Blood or tissue specimen
Basic Attributes
- Class
- MOLPATH
- Type
- Laboratory
- First Released
- Version 2.69
- Last Updated
- Version 2.69
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Gen MSH6 estudio delecion+duplicacion y estudio mutacional completo: |
es-MX | Spanish (Mexico) | Deleción del gen MSH6 + duplicación y análisis de mutación completo: |
fr-FR | French (France) | MSH6 gène délétion+duplication et analyse complète des mutations: |
it-IT | Italian (Italy) | MSH6, gene Delezione+duplicazione & analisi di mutazione completa: Synonyms: delezione e duplicazione Gene MSH6 Genetica molecolare Osservazione Patologia molecolare Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & |
nl-NL | Dutch (Netherlands) | MSH6-gen deletie + duplicatie & volledige mutatie analyse: Synonyms: molgen MSH6 gen |
tr-TR | Turkish (Turkey) | MSH6 geni delesyon+duplikasyon ve tam mutasyon analizi: Synonyms: çiftleme |
zh-CN | Chinese (China) | MSH6 基因 缺失+重复与全面的突变分析: Synonyms: G/T 错配-结合蛋白(G/T mismatch-binding protein, |
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