96316-5
AMPAR1+AMPAR2 IgG Ab [Titer] in Serum by Cell binding immunofluorescent assay
Active
Part Descriptions
LP230508-6 Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor 1+2
Alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptor 1 (AMPAR1) and AMPA receptor 2 (AMPAR2) antibodies target the AMPA receptor, an ionotropic glutamate receptor and key excitatory neurotransmitter. AMPA receptors are comprised of different combinations of four glutamate receptor subunits called GluA1-GluA4 (also known as GluR1-GluR4 and GluR-A to GluR-D). They are vital for brain development and function, such as memory and cognitive development. Detection of antineuronal autoantibodies against AMPA receptors aids in the diagnosis of autoimmune encephalopathies, especially limbic encephalitis, and related conditions. PMCID: PMC4478035 The presence of AMPA antibodies may also indicate an undiscovered tumor in the thymus, lung or breast. PMID: 23983888 The neurological symptoms associated with AMPA receptor 1 antibodies include altered mental status, convulsions, memory loss amnesia, auditory hallucinations, limbic encephalitis, abnormal behavior, schizophrenia, dizziness and hyperthermia. The neurological symptoms associated with AMPA receptor 2 antibodies include seizures, short-term memory loss, limbic encephalitis, altered mental status, chorea and facial dyskinesia. PMID: 24707504
Source: Regenstrief LOINC
LP269367-1 CBA IFA
In cell binding assays or cell-based assays (CBA) also known as cell-based immunoassays, the DNA coding for a particular antigen is transfected into cultured cells, which are then used directly as substrate for antibody detection by immunofluorescence. The advantage of CBA IFA over conventional immunoassays is that purification and stability of the antigen is not required and they provide an in vivo substrate.
Source: Regenstrief LOINC,
Fully-Specified Name
- Component
- Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor 1+2 Ab.IgG
- Property
- Titr
- Time
- Pt
- System
- Ser
- Scale
- SemiQn
- Method
- CBA IFA
Additional Names
- Short Name
- AMPAR 1+2 IgG Titr Ser CBA IFA
- Display Name
- AMPAR1+AMPAR2 IgG Cell binding immunofluorescent assay (S) [Titer]
- Consumer Name Alpha Get Info
- AMPAR1+AMPAR2 IgG antibody, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.69
- Last Updated
- Version 2.75
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Receptores de Alfa-amino-3 hidroxi-5-metil-4-isoxazolpropionato 1 y 2 IgG: Synonyms: Semicuantitativo |
es-MX | Spanish (Mexico) | Receptor 1 + 2 Ab.IgG de alfa-amino-3-hidroxi-5-metil-4-isoxazolpropionato: |
fr-FR | French (France) | AMPA récepteur 1+2 anticorps IgG: |
it-IT | Italian (Italy) | Recettore tipo 1+2 per alfa-amino-3-idrossi-5metil-4-isoxazolepropionato Ab.IgG: Synonyms: AMPAR1 AMPAR1+AMPAR2 anticorpi IgG anticorpo Fluorescenza indiretta degli anticorpi (IFA) Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant Titolo |
zh-CN | Chinese (China) | Alpha-氨基-3-羟基-5-甲基-4-异噁唑丙酸受体 1+2 抗体.IgG: Synonyms: Ⅰ Ⅱ Ⅲ Ab.IgG; |
Example Units
Unit | Source |
---|---|
{titer} | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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