LOINC
Version 2.73

96368-6Pregabalin [Presence] in Saliva (oral fluid) by Confirmatory methodActive

Part Descriptions

LP61621-6   Pregabalin
Pregabalin (brand name Lyrica) is an anticonvulsant gamma-aminobutyric acid analog drug used for neuropathic pain and as an adjunct therapy for partial seizures with or without secondary generalization in adults. It has also been found effective for generalized anxiety disorder. Studies have shown that pregabalin is effective at treating chronic pain in disorders such as fibromyalgia and spinal cord injury. It was designed as a more potent successor to gabapentin, and considered to have a low potential for abuse and limited dependence liability if misused. [PubChem:Pregabalin] Source: Regenstrief LOINC

LP7565-7   Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin.[PMID:17268583] Source: Regenstrief LOINC

LP262420-5   Saliva DRUG/TOX
Oral fluid (or saliva) is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. The test procedures that use oral fluid for drug screening are usually similar to those for other specimens but adapted for oral fluid. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Drugs present in oral fluid are often the parent drug rather than a metabolite and tests kits reflect those differences. Concentrations of cocaine, amphetamines and some opioids in oral fluid are either similar or higher than concentrations in plasma. The concentration of tetrahydrocannabinol (THC) in oral fluid is similar to that of plasma, though in cases where recent ingestion has occurred, levels may be higher due to the significant local absorption in the oral cavity. Confirmatory testing on oral fluid using liquid chromatography-mass spectrometry (LC-MS) is highly sensitive and specific even on relatively small sample sizes. An increased understanding of pharmacokinetics in oral fluid has flourished inover the last ten years has allowed the correlation of . As a result, the concentrations of various drugs in oral fluid have been correlated to blood concentrations and the effects they have on the individual.[PMID:17268583] Source: Regenstrief LOINC

Fully-Specified Name

Component
Pregabalin
Property
PrThr
Time
Pt
System
Saliva
Scale
Ord
Method
Confirm

Additional Names

Short Name
Pregabalin Sal Ql Cfm
Display Name
Pregabalin Confirm Ql (Sal)
Consumer Name Alpha
Pregabalin, Saliva

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.69
Last Updated
Version 2.69
Order vs. Observation
Both

Member of these Groups

LG37665-3 Pregabalin|ANYProp|ANYTm|ANYSys|ANYMeth

Language Variants Get Info

zh-CNChinese (China)
普瑞巴林:存在情况或阈值:时间点:唾液:序数型:毒理学确认试验
nl-NLDutch (Netherlands)
pregabaline:aanwezigheid:moment:speeksel:ordinaal:bevestiging
et-EEEstonian (Estonia)
Pregabaliin:PrThr:Pt:Sal:Ord:Kinnitav
fr-BEFrench (Belgium)
Prégabaline:PrThr:Temps ponctuel:Salivaire:Ordinal:Confirmé
fr-CAFrench (Canada)
Prégabaline:Présence-Seuil:Temps ponctuel:Salivaire:Ordinal:Confirmation
fr-FRFrench (France)
Prégabaline:Présence/Seuil:Ponctuel:Salive:Qualitatif:Confirmation
it-ITItalian (Italy)
Pregabalin:PrThr:Pt:Saliva:Ord:Conferma
ru-RURussian (Russian Federation)
Прегабалин:PrThr:ТчкВрм:Слюна:Пор:Подтверждать
es-MXSpanish (Mexico)
Pregabalina:Presencia o umbral:Punto temporal:Saliva:Ordinal:Confirmar
es-ESSpanish (Spain)
Pregabalina:PrThr:Punto temporal:Saliva:Ord:Confirmatorio
tr-TRTurkish (Turkey)
Pregabalin:MevcEşik:Zmlı:Tükürük:Srl:Onay

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=96368-6