Version 2.72

96960-0Varicella zoster virus IgM Ab index [Units/volume] in Serum and CSFActive

Part Description

LP14853-3   Varicella zoster virus
Varicella zoster virus (VZV) is a double-stranded alphaherpesvirus that causes seasonal outbreaks of chickenpox and shingles in non-immunized populations. VZV is highly infectious and is transmitted by contact with the ruptured fluid filled blisters and respiratory secretions of infected individuals. Immunity post infection is usually lifelong though the latent virus inhabits the sensory nerve ganglia where it can reactivate causing shingles when immunity declines with aging.[http://jvi.asm.org/content/88/24/13936.full] In the over fifty strains of VZV that have been sequenced it has been found that a single nucleotide polymorphism occurs about every 100 bases. The patterns of polymorphisms in VZV correlate with different geographical regions of infection and is the basis for the classification of viral clades.[https://grose.lab.uiowa.edu/vzv-genomes-and-evolution] Breuer proposed the nomenclature for the VZV clades as 1-5 with the suspected clades VI and VII to be confirmed later. The geographical regions associated with the seven clades are as follows:
Clades 1 and 3-represent the dominant clades of the circulating VZV in Europe and the Americas
Clades 4 and 5-found in Africa
Clade VI found in France, Italy
Clade VII exclusively isolated in the US
Clade 2-Asia from Korea, Japan, China not found in India, Nepal and Bangladesh where clades 4 and 5 were dominant
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054591/ Source: Regenstrief LOINC

Fully-Specified Name

Varicella zoster virus Ab.IgM Index

Additional Names

Short Name
VZV IgM Index Ser+CSF-aCnc
Display Name
VZV IgM index Qn (S+CSF)
Consumer Name Alpha
Varicella zoster virus (VZV; Chickenpox) IgM index, Serum+Cerebrospinal fluid

Basic Attributes

First Released
Version 2.70
Last Updated
Version 2.70
Order vs. Observation

Formula (Readable)

VZV IgM Index = (CSF VZV IgM/CSF total IgM)/(Serum VZV IgM/Serum total IgM)

Member of these Groups

LG32750-8 Varicella zoster virus

Language Variants Get Info

zh-CNChinese (China)
水痘带状疱疹病毒 抗体.IgM 指数:任意型浓度:时间点:血清+脑脊液:定量型:
nl-NLDutch (Netherlands)
varicella-zostervirus As.IgM-index:eenheid/volume:moment:serum en liquor cerebrospinalis:kwantitatief:
et-EEEstonian (Estonia)
Tuulerõugeviirus Antikehad.IgM indeks:Acnc:Pt:S+CSF:Qn:
fr-BEFrench (Belgium)
Virus varicelle-zona Anticorps. Indice IgM:Concentration arbitraire:Temps ponctuel:Sérum+LCR:Quantitatif:
fr-CAFrench (Canada)
Virus varicelle-zona , Indice IgM:Concentration arbitraire:Temps ponctuel:Sérum+LCR:Quantitatif:
it-ITItalian (Italy)
Varicella zoster, virus Ab.indice IgM:ACnc:Pt:Siero+LCS:Qn:
ru-RURussian (Russian Federation)
Varicella zoster вирус Ат.IgM индекс:ПроизвКонц:ТчкВрм:Сыв+ЦСЖ:Колич:
es-MXSpanish (Mexico)
Índice Ab.IgM del virus de la varicela zóster:ACnc:Punto temporal:Ser + CSF:Cuantitativo:
es-ESSpanish (Spain)
Virus Varicella zoster Indice IgM:Concentración arbitraria:Punto temporal:Suero y Líquido Cefalorraquideo simultaneamente:Qn:
tr-TRTurkish (Turkey)
Varicella zoster virüsü Ab.IgM index:SçKons:Zmlı:Ser+BOS:Kant:

Example Units

Unit Source
{Index_val} Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info