LOINC
Version 2.70

97235-6Cocaine [Presence] in Cord tissue by Confirmatory methodActive

Part Descriptions

LP16048-8   Cocaine
Cocaine is an alkaloid of Erythroxylon coca that is grown in the northern South American Andes, India, Africa and Java. It is used medicinally as a local anesthetic and vasoconstrictor in nasal surgery and to dilate pupils. Because cocaine is a powerful central nervous system stimulant it is among the most abused drugs. Cocaine abuse can lead to sudden death due to cardiotoxicity or the sequential development of hyperthermia, agitated delirium and respiratory arrest. Cocaine is metabolized in the liver to inactive benzoylecgonine (BZE). BZE is pharmacologically inactive and has a longer half-life than its parent drug cocaine. It is the substance most tested for when investigating suspected cocaine abuse. Cocaethylene (CE) is produced in the liver in the presence of ethanol and has been shown to have similar stimulatory effects as cocaine in animal studies.(Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, Seventh Edition) Cocaethylene is toxic to the myocardium. [PMID: 8761012] Source: Regenstrief LOINC

LP16048-8   Cocaine
An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake. Source: National Library of Medicine, MeSH 2006

Fully-Specified Name

Component
Cocaine
Property
PrThr
Time
Pt
System
TissCo
Scale
Ord
Method
Confirm

Additional Names

Short Name
Cocaine TissCo Ql Cfm
Display Name
Cocaine Confirm Ql (Umb cord tissue)
Consumer Name Alpha
Cocaine, Umbilical cord tissue

Example Answer List LL744-4

Source: Regenstrief Institute

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.70
Last Updated
Version 2.70
Order vs. Observation
Both

Member of these Groups

LG37611-7 Cocaine|ANYProp|ANYTm|ANYSys|ANYMeth

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