LOINC
Version 2.73

98063-1Beta-lactam resistance ESBL blaCTX-M-15 gene [Presence] by Molecular methodActive

Term Description

Qualitative detection of nucleic acids within the beta-lactamase CTX-M-15 gene (blaCTX-M-15) found in Gram-negative bacteria. Testing may be performed in addition to conventional culture susceptibility testing to determine the potential bacterial resistance mechanism to antibiotics.
Source: Regenstrief LOINC

Part Description

LP426518-9   Bacterial beta-lactam resistance ESBL blaCTX-M-15 gene
Extended-spectrum beta-lactamases (ESBL) are enzymes produced by some bacteria that are resistant to the majority of beta-lactam antibiotics which include the penicillins, cephalosporins and the monobactam aztreonam. [https://www.uptodate.com/contents/extended-spectrum-beta-lactamases] Organisms producing CTX-M type ESBL enzymes have been isolated worldwide with more than 150 enzymes identified. These enzymes have been classified into seven major phylogenetic groups: CTX-M -1, CTX-M-2, CTX-M-8, CTX-M-9, CTX-M-25, CTX-M-74 and CTX-M-75. CTX-M-9 group includes CTX-M-14 and CTX-M-15. The rare ESBL type CTX-M-8 has been isolated in Germany, mainly in E. coli, but also in Salmonella and E. aerogenes. CTX-M type ESBL have been isolated worldwide and their incidence has increased dramatically and is still increasing leading to a major therapeutic issue. Currently more than 150 allelic variants of CTX-M have been identified. The dissemination of these enzymes has caused an increased use of carbapenems for treatment of infections which carries its own risk of furthering resistance. [PMID:25234380] The genes are named with the prefix "bla", which stands for "beta-lactam", followed by the enzyme, for example, blaCTX-M-1. Source: LOINC

Fully-Specified Name

Component
Bacterial beta-lactam resistance ESBL blaCTX-M-15 gene
Property
PrThr
Time
Pt
System
Isolate/Specimen
Scale
Ord
Method
Molgen

Additional Names

Short Name
ESBL blaCTX-M-15 gene Islt/Spm Ql
Display Name
Beta-lactam resistance ESBL blaCTX-M-15 gene Molgen Ql (Islt/Spec)
Consumer Name Alpha
Beta-lactam resistance ESBL blaCTX-M-15 gene

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.70
Last Updated
Version 2.72
Order vs. Observation
Observation

Language Variants Get Info

zh-CNChinese (China)
细菌 beta-内酰胺耐药 ESBL blaCTX-M-15 基因:存在情况或阈值:时间点:分离株/标本:序数型:分子遗传学类实验室方法
nl-NLDutch (Netherlands)
bacteriële bètalactamresistentie ESBL blaCTX-M-15-gen:aanwezigheid:moment:isolaat of monster:ordinaal:moleculair genetisch onderzoek
it-ITItalian (Italy)
Resistenza batterica beta-lactamica, gene ESBL blaCTX-M-15:PrThr:Pt:Isolato/Campione:Ord:Molgen
es-MXSpanish (Mexico)
Resistencia bacteriana a betalactámicos BLEE gen blaCTX-M-15:PrThr:Punto temporal:Aislar / Muestra:Ordinal:Molgen
es-ESSpanish (Spain)
gen bacteriano ESBL blaCTX-M-15 resistente a betalactámicos:PrThr:Punto temporal:Muestra aislada:Ord:Genética molecular

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=98063-1