LOINC
Version 2.71

98122-5Neutrophil.fMLP and PMA stimulated DHR panel by Flow cytometry (FC)Active

Term Description

The phorbol myristate acetate (PMA) and N-formyl-methionyl-leucyl-phenylalanine (fMLP) stimulated neutrophil dihydrorhodamine (DHR) test assesses neutrophil activation and NADPH oxidase function when stimulated by PMA and fMLP (different populations of neutrophils are stimulated by PMA and fMLP, respectively). This test is used to diagnose chronic granulomatous disease (CGD) and complete myeloperoxidase deficiency; monitor chimerism and NADPH oxidase function after stem cell transplant, assess NADPH oxidase activity prior to transplant; identify and monitor chromosome X inactivation changes with age in carrier females with X-linked CGD; and diagnose Rac2 deficiency.
To report results for the fMLP stimulated neutrophil DHR test alone, use [LOINC: 93123-3]. To report results for the PMA stimulated neutrophil DHR test alone, use [LOINC: 98124-1].
Source: Regenstrief LOINC

Panel Hierarchy
Details for each LOINC in Panel LHC-Forms

LOINC Name R/O/C Cardinality Example UCUM Units
98122-5 Neutrophil.fMLP and PMA stimulated DHR panel by Flow cytometry (FC)
Indent85370-5 Neutrophil.fMLP stimulated.DHR mean fluorescence intensity in Blood by Flow cytometry (FC) [arb'U]
Indent85371-3 Neutrophil.fMLP stimulated.DHR mean fluorescence intensity in Control Blood by Flow cytometry (FC) [arb'U]
Indent85372-1 Neutrophil.fMLP stimulated.DHR/Neutrophil.fMLP stimulated.total in Control Blood by Flow cytometry (FC) %
Indent85373-9 Neutrophil.fMLP stimulated.DHR/Neutrophil.fMLP stimulated.total in Blood by Flow cytometry (FC) %
Indent85374-7 Neutrophil.PMA stimulated.DHR mean fluorescence instensity in Blood by Flow cytometry (FC) [arb'U]
Indent85375-4 Neutrophil.PMA stimulated.DHR mean fluorescence instensity in Control Blood by Flow cytometry (FC) [arb'U]
Indent85376-2 Neutrophil.PMA stimulated.DHR/Neutrophil.PMA stimulated.total in Blood by Flow cytometry (FC) %
Indent85377-0 Neutrophil.PMA stimulated.DHR/Neutrophil.PMA stimulated.total in Control Blood by Flow cytometry (FC) %
Indent85369-7 Neutrophils [#/volume] in Control Blood by Flow cytometry (FC) /uL
Indent751-8 Neutrophils [#/volume] in Blood by Automated count 10*3/uL

Fully-Specified Name

Component
Neutrophil.fMLP & PMA stimulated DHR panel
Property
-
Time
Pt
System
^Patient
Scale
-
Method
Flow cytometry

Additional Names

Short Name
Neut fMLP + PMA stim DHR Pnl Patient FC
Display Name
Neutrophil.fMLP and PMA stimulated DHR panel FC
Consumer Name Alpha
Neutrophil.fMLP and PMA stimulated DHR panel

Basic Attributes

Class
PANEL.HEM/BC
Type
Laboratory
First Released
Version 2.71
Last Updated
Version 2.71
Order vs. Observation
Order
Panel Type
Panel

LOINC FHIR® API Example - CodeSystem and Questionnaire Requests Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=98122-5 https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/98122-5