99112-5
Rocio virus neutralizing antibody [Titer] in Specimen by Neutralization test
Active
Part Descriptions
LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method.
Source: Regenstrief LOINC
LP421091-2 Rocio virus
Rocio virus (ROCV) was isolated in 1975 during an outbreak of human encephalitis in Brazil. ROCV is an enveloped flavivirus containing a positive-sense single-stranded RNA PMID: 28939977. ROCV belongs to the Flaviviridae family, genus Flavivirus [NCBI Taxonomy: 64315]. Like other flaviviruses ROCV is morphologic, morphogenetic, and can cross the blood brain barrier. ROCV infection presents as fever, malaise, severe headache, lower extremity weakness, and severe neurologic symptoms including encephalitis PMID: 28939977. The vectors are mosquitoes and may include Aedes scapularis and Psorophora ferox [Researchgate:318323245].
Source: Regenstrief LOINC,
LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Rocio virus Ab.Neut
- Property
- Titr
- Time
- Pt
- System
- XXX
- Scale
- SemiQn
- Method
- Neut
Additional Names
- Short Name
- Rocio virus NAb Titr Spec Nt
- Display Name
- Rocio virus neut ab Neut test (Specimen) [Titer]
- Consumer Name Alpha Get Info
- Rocio virus neutralizing antibody, Specimen
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.72
- Last Updated
- Version 2.75
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Rocio-Virus Ak.neutralisierend: |
es-ES | Spanish (Spain) | Virus Rocio Anticuerpos antineutrófilos: Synonyms: Semicuantitativo |
fr-FR | French (France) | Rocio virus Ac neutralisant: |
it-IT | Italian (Italy) | Rocio virus Ab.Neut: Synonyms: anticorpo Microbiologia Punto nel tempo (episodio) ROCV Test di neutralizzazione Titolo |
nl-NL | Dutch (Netherlands) | Rocio-virus As.neutraliserend: Synonyms: antistof; |
pl-PL | Polish (Poland) | Wirus Rocio Ab.Neutralizujące: Synonyms: Przeciwciała neutralizujące do wirusa Rocio |
zh-CN | Chinese (China) | 罗西奥病毒 抗体.中和: Synonyms: Ab; |
Example Units
Unit | Source |
---|---|
{titer} | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=99112-5
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright