99121-6
Rift valley fever virus neutralizing antibody [Titer] in Specimen by Neutralization test
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Part Descriptions
LP19936-1 Rift valley fever virus
Rift Valley Fever (RVF) is a viral zoonosis (affects primarily domestic livestock, but can be passed to humans) causing fever. It is spread by the bite of infected mosquitoes. The disease is caused by the RVF virus, a member of the genus Phlebovirus (family Bunyaviridae). The disease was first reported among livestock in Kenya around 1915, but the virus was not isolated until 1931. RVF outbreaks occur across sub-Saharan Africa, with outbreaks occurring elsewhere infrequently (but sometimes severely - in Egypt in 1977 -78, several million people were infected and thousands died during a violent epidemic; in September 2000 an outbreak was confirmed in Saudi Arabia and Yemen). In humans the virus can cause several different syndromes. Usually sufferers have either no symptoms or only a mild illness with fever, headache, myalgia and liver abnormalities.
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Source: Wikipedia, Rift valley fever virus (Wikipedia)
LP19936-1 Rift valley fever virus
A mosquito-borne species of the PHLEBOVIRUS genus found in eastern, central, and southern Africa, producing massive hepatitis, abortion, and death in sheep, goats, cattle, and other animals. It also has caused disease in humans.
Source: National Library of Medicine, MeSH 2006
LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method.
Source: Regenstrief LOINC
LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Rift Valley fever virus Ab.Neut
- Property
- Titr
- Time
- Pt
- System
- XXX
- Scale
- SemiQn
- Method
- Neut
Additional Names
- Short Name
- RVFV NAb Titr Spec Nt
- Display Name
- Rift valley fever virus neut ab Neut test (Specimen) [Titer]
- Consumer Name Alpha Get Info
- Rift Valley Fever virus neutralizing antibody, Specimen
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.72
- Last Updated
- Version 2.75
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Rift-Valley-Fieber-Virus Ak.neutralisierend: Synonyms: RVFV |
es-ES | Spanish (Spain) | Virus de la fiebre del valle del Rift Anticuerpos antineutrófilos: Synonyms: Semicuantitativo |
fr-FR | French (France) | Fièvre de la vallée du rift virus Ac neutralisant: |
fr-CA | French (Canada) | Virus fièvre Vallée du Rift Ac.neut: |
it-IT | Italian (Italy) | Febbre della valle del Rift, virus Ab.Neut: Synonyms: anticorpo Microbiologia Punto nel tempo (episodio) Test di neutralizzazione Titolo Virus della febbre della valle del Rift |
nl-NL | Dutch (Netherlands) | Riftdalkoortsvirus As.neutraliserend: Synonyms: antistof; |
pl-PL | Polish (Poland) | Wirus gorączki Doliny Rift Ab.Neutralizujące: Synonyms: Przeciwciała do wirusa gorączki Doliny Rift Przeciwciała neutralizujące do wirusa gorączki Doliny Rift Wirus RVF |
zh-CN | Chinese (China) | 裂谷热病毒 抗体.中和: Synonyms: Ab; |
Example Units
Unit | Source |
---|---|
{titer} | Example UCUM Units |
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- CodeSystem lookup
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