Version 2.77

Part Descriptions

LP207365-0   Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method. Source: Regenstrief LOINC

LP421087-0   Tick-borne encephalitis virus
Tick-borne encephalitis virus (TBEV) is a single-stranded RNA virus that causes an infectious disease of the central nervous system. TBEV has 3 subtypes: European (milder disease), Siberian (more severe), and Far Eastern (more chronic). The disease most often manifests as meningitis, encephalitis, or meningoencephalitis. Although TBE is most commonly recognized as a neurological disorder, mild fever can also occur. Long-lasting or permanent neuropsychiatric symptoms are observed in 10-20% of infected patients. Diagnosis of TBE is usually determined by the presence of TBEV-specific IgM and IgG antibodies in serum or cerebral spinal fluid by enzyme-linked immuno-sorbent assay (ELISA). Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Tick-borne encephalitis (Wikipedia)

LP6416-4   Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804 Source: Regenstrief LOINC

Fully-Specified Name

Component
Tick-borne encephalitis virus Ab.Neut
Property
Titr
Time
Pt
System
XXX
Scale
SemiQn
Method
Neut

Additional Names

Short Name
TBEV NAb Titr Spec Nt
Display Name
Tick-borne encephalitis virus neut ab Neut test (Specimen) [Titer]
Consumer Name Alpha Get Info
Tick-borne encephalitis virus neutralizing antibody, Specimen

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.72
Last Updated
Version 2.75
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Virus de la encefalitis transmitida por garrapatas Anticuerpos antineutrófilos:Titulo / Factor de dilución:Punto temporal:XXX:Semicuantitativo:Prueba de neutralización
Synonyms: Semicuantitativo
fr-FR French (France) Encéphalite à tique virus Ac neutralisant:Titre:Ponctuel:Milieux divers:Numérique:Neutralisation
it-IT Italian (Italy) Encefalite trasmessa da zecca, virus Ab.Neut:Titr:Pt:XXX:SemiQn:Neut
Synonyms: anticorpo Microbiologia Punto nel tempo (episodio) Test di neutralizzazione Titolo Virus dell''encefalite trasmessa da zecca
nl-NL Dutch (Netherlands) tekenencefalitisvirus As.neutraliserend:titer:moment:XXX:semikwantitatief:neutralisatietest
Synonyms: antistof; antilichaam TBEV; tickborne-encefalitisvirus
pl-PL Polish (Poland) Wirus kleszczowego zapalenia mózgu Ab.Neutralizujące:miano:punkt w czasie:XXX:półilościowy:test neutralizacji
Synonyms: Przeciwciała neutralizujące do wirusa kleszczowego zapalenia mózgu
zh-CN Chinese (China) 蜱传脑炎病毒 抗体.中和:滴定度:时间点:XXX:半定量型:中和试验
Synonyms: Ab;自身抗体 TBEV 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项 中和试验;中和抗体;中和 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 壁虱;扁虱;羊虱 大脑炎 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间 脑炎（Encephalitis，大脑炎） 脑脊髓炎 脑脊髓炎（Encephalomyelitis）

Example Units

Unit Source
{titer} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=99124-0