99435-0
Cyprinus carpio recombinant (rCyp c) 1 IgG4 Ab [Mass/volume] in Serum
Active
Part Descriptions
LP128513-1 Cyprinus carpio recombinant (rCyp c) 1
Cyp c 1 is a major fish protein, a parvalbumin. Parvalbumins are small, acidic calcium-binding buffer proteins found in fast muscle of lower and higher vertebrates. They are thought to be involved in the relaxation process in fast-twitch muscle. They have been identified as the major fish allergens. This is the basis for the use of recombinant Carp parvalbumin as a tool for in vitro and in vivo diagnosis of fish allergy. Carp parvalbumin is a 3 EF-hand calcium-binding protein. It has remarkable stability, which explains why, despite cooking and exposure to the gastrointestinal tract, it (along with other paralbumins) can sensitise patients.
Copyright Copyright © 2006 Phadia AB.
Source: ImmunoCap, ImmunoCap
LP32397-9 Ab.IgG4
IgG4 is the least common subtype of IgG, and it has a variety of functions. In the context of allergic disease it is thought to have an immune-inhibitory role in preventing anaphylaxis and is commonly known as a "blocking" antibody. IgG4 binding to an allergen can compete with IgE-mediated binding, thereby inhibiting the activation of mast cells and basophils and IgE-mediated presentation to T-cells. Measuring IgG4 and its ratio to IgE has a role in monitoring allergen specific immunotherapy PMID: 26023323. IgG4 is also thought to have a role in autoimmunity and be involved in a less defined entity known as IgG4-Related Disease, a chronic immune-mediated fibroinflammatory disorder that often manifests with tumor-like masses .[https://www.merckmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/igg4-related-disease/igg4-related-disease]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Cyprinus carpio recombinant (rCyp c) 1 Ab.IgG4
- Property
- MCnc
- Time
- Pt
- System
- Ser
- Scale
- Qn
- Method
Additional Names
- Short Name
- Carp (rCyp c) 1 IgG4-mCnc
- Display Name
- Carp recombinant (rCyp c) 1 IgG4 (S) [Mass/Vol]
- Consumer Name Alpha Get Info
- Carp recombinant (rCyp c) 1 IgG4 antibody
Basic Attributes
- Class
- ALLERGY
- Type
- Laboratory
- First Released
- Version 2.72
- Last Updated
- Version 2.72
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Cyprinus carpio recombinante (rCyp c) 1 IgG4: Synonyms: Cuantitativo |
fr-FR | French (France) | Carpe commune rCyp c1 (recombinant) Ac IgG4: |
it-IT | Italian (Italy) | Cyprinus carpio, ricombinante (rCyp c) 1 Ab.IgG4: Synonyms: Anticorpi IgG4 anticorpo Concentrazione di Massa Punto nel tempo (episodio) Ricombinante (rCyp c) 1 di carpa (Cyprinus carpio) Risposta agli antigeni Siero |
nl-NL | Dutch (Netherlands) | Cyprinus carpio recombinant (rCyp c) 1 As.IgG4: Synonyms: antistof; |
ru-RU | Russian (Russian Federation) | Cyprinus carpio рекомбинантный (rCyp c) 1 Ат.IgG4: Synonyms: Антитело Карп (Cyprinus carpio) рекомбинантный (rCyp c) 1 Количественный Массовая концентрация Сыворотка Точка во времени; |
tr-TR | Turkish (Turkey) | Cyprinus carpio recombinant (rCyp c) 1 Ab.IgG4: Synonyms: Ak Ak.IgG4 |
zh-CN | Chinese (China) | 鲤鱼 重组 (rCyp c) 1 抗体.IgG4: Synonyms: Ⅰ Ab.IgG4; |
Example Units
Unit | Source |
---|---|
mg/L | Example UCUM Units |
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LOINC Copyright
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