99438-4
English walnut recombinant (rJug r) 3 IgG4 Ab [Mass/volume] in Serum
Active
Part Descriptions
LP212207-7 Juglans regia recombinant (rJug r) 3
Allergy to walnut is among the most common allergy of all tree nuts. Allergic reactions to walnut can be severe and sensitivity is seldom outgrown. The rJug r 3 is a recombinant protein of the walnut and is a lipid transfer protein. Lipid transfer proteins are often linked to severe allergic reactions. They are present in many species of plants which can lead to cross-reactivity with other foods including the peach, other nuts, apples or grapes. Patients who are allergic to Jug r 3 are at risk of reacting to other lipid transfer proteins. (http://www.phadia.com/en/Products/Allergy-testing-products/ImmunoCAP-Allergen-Information/Food-of-Plant-Origin/Allergen-Components/rJug-r-3-Walnut/)
Source: Regenstrief LOINC
LP32397-9 Ab.IgG4
IgG4 is the least common subtype of IgG, and it has a variety of functions. In the context of allergic disease it is thought to have an immune-inhibitory role in preventing anaphylaxis and is commonly known as a "blocking" antibody. IgG4 binding to an allergen can compete with IgE-mediated binding, thereby inhibiting the activation of mast cells and basophils and IgE-mediated presentation to T-cells. Measuring IgG4 and its ratio to IgE has a role in monitoring allergen specific immunotherapy PMID: 26023323. IgG4 is also thought to have a role in autoimmunity and be involved in a less defined entity known as IgG4-Related Disease, a chronic immune-mediated fibroinflammatory disorder that often manifests with tumor-like masses .[https://www.merckmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/igg4-related-disease/igg4-related-disease]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Juglans regia recombinant (rJug r) 3 Ab.IgG4
- Property
- MCnc
- Time
- Pt
- System
- Ser
- Scale
- Qn
- Method
Additional Names
- Short Name
- English walnut (rJug r) 3 IgG4-mCnc
- Display Name
- English walnut recombinant (rJug r) 3 IgG4 (S) [Mass/Vol]
- Consumer Name Alpha Get Info
- English walnut recombinant (rJug r) 3 IgG4 antibody
Basic Attributes
- Class
- ALLERGY
- Type
- Laboratory
- First Released
- Version 2.72
- Last Updated
- Version 2.72
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Recombinante (rJug r) 3 Juglans regia IgG4: Synonyms: Cuantitativo |
fr-CA | French (Canada) | Noix rjug r3 (recombinant) , IgG4: |
fr-FR | French (France) | Noix rjug r3 (recombinant) Ac IgG4: |
it-IT | Italian (Italy) | Juglans regia ricombinante (rJug r) 3 Ab.IgG4: Synonyms: Anticorpi IgG4 anticorpo Concentrazione di Massa Noce bianco Punto nel tempo (episodio) Risposta agli antigeni Siero |
nl-NL | Dutch (Netherlands) | Juglans regia recombinant (rJug r) 3 As.IgG4: Synonyms: antistof; |
zh-CN | Chinese (China) | 核桃 重组 (rJug r) 3 抗体.IgG4: Synonyms: Ⅲ Ab.IgG4; |
Example Units
Unit | Source |
---|---|
mg/L | Example UCUM Units |
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