Version 2.77

Part Descriptions

LP220394-3   Anacardium occidentale recombinant (rAna o) 3
Anacardium occidentale (Ana o) 3 is a 2S albumin and a major allergen of cashew nuts that elicits an allergic response in 81% of people with a sensitivity to cashews. 2S albumins have a very stable intrinsic structure that is preserved even in harsh environments, such as the gastrointestinal tract where it is believed to initiate an immune response. Due to its resistance to both hydrolysis in the intestinal tract and denaturation by heat, Ana o 3 is considered a very potent allergen.(http://www.phadia.com/es/5/Productos/ImmunoCAP-Allergens/Food-of-Plant-Origin/Allergen-Components/rAna-o-3-Cashew-nut/) Three native large subunit isoforms of recombinant Ana o 3 have been identified to have 16 reactive peptides, four of which produce strong signals. One isoform shares a fair amount of homology with a walnut isoform and offers a basis for cross-reactivity of walnut with the Ana o 3 isotope. PMID: 15940148 Source: Regenstrief LOINC

LP32397-9   Ab.IgG4
IgG4 is the least common subtype of IgG, and it has a variety of functions. In the context of allergic disease it is thought to have an immune-inhibitory role in preventing anaphylaxis and is commonly known as a "blocking" antibody. IgG4 binding to an allergen can compete with IgE-mediated binding, thereby inhibiting the activation of mast cells and basophils and IgE-mediated presentation to T-cells. Measuring IgG4 and its ratio to IgE has a role in monitoring allergen specific immunotherapy PMID: 26023323. IgG4 is also thought to have a role in autoimmunity and be involved in a less defined entity known as IgG4-Related Disease, a chronic immune-mediated fibroinflammatory disorder that often manifests with tumor-like masses .[https://www.merckmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/igg4-related-disease/igg4-related-disease] Source: Regenstrief LOINC

Fully-Specified Name

Component
Anacardium occidentale recombinant (rAna o) 3 Ab.IgG4
Property
MCnc
Time
Pt
System
Ser
Scale
Qn
Method

Additional Names

Short Name
Cashew nut (rAna o) 3 IgG4-mCnc
Display Name
Cashew nut recombinant (rAna o) 3 IgG4 (S) [Mass/Vol]
Consumer Name Alpha Get Info
Cashew nut recombinant (rAna o) 3 IgG4 antibody

Basic Attributes

Class
ALLERGY
Type
Laboratory
First Released
Version 2.72
Last Updated
Version 2.72
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Recombimante rAna o 3. Cashew nut (Anacardium occidentale) IgG4:Concentración de masa:Punto temporal:Suero:Qn:
Synonyms: Cuantitativo
fr-FR French (France) Noix de cajou rAna o3 (recombinant) Ac IgG4:Masse/Volume:Ponctuel:Sérum:Numérique:
it-IT Italian (Italy) Anacardium occidentale, ricombinante (rAna o) 3 Ab.IgG4:MCnc:Pt:Siero:Qn:
Synonyms: Anacardio (Anacardium occidentale) Anticorpi IgG4 anticorpo Concentrazione di Massa Punto nel tempo (episodio) Ricombinante (rAna o) 3 di anacardio (Anacardium o Risposta agli antigeni Siero
nl-NL Dutch (Netherlands) cashewnoot (Anacardium occidentale) recombinant (rAna o) 3 As.IgG4:massa/volume:moment:serum:kwantitatief:
Synonyms: antistof; antilichaam cashewnoot
pl-PL Polish (Poland) Anacardium occidentale rekombinowany (rAna o) 3 Ab.IgG4:stężenie masowe:punkt w czasie:surowica:ilościowy:
Synonyms: Nanercz zachodni (anacardium occidentale) Przeciwciała IgE do komponenty alergenowej Ana o 3 orzecha nanercza zachodniego (anacardium occidentale)
zh-CN Chinese (China) 腰果 重组 (rAna o) 3 抗体.IgG4:质量浓度:时间点:血清:定量型:
Synonyms: Ⅲ Ab.IgG4;IgG4;抗体 IgG4 Ab;自身抗体 III 三 叁 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 水平;浓度;质量浓度(单位体积) 漆树实;腰果仁;贾如树坚果;贾如树种子

Example Units

Unit Source
mg/L Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=99439-2