99440-0
Peanut recombinant (rAra h) 6 IgG4 Ab [Mass/volume] in Serum
Active
Part Descriptions
LP263675-3 Arachis hypogaea recombinant (rAra h) 6
Ara h 6 is a 2S albumin seed storage protein and clinically relevant peanut allergen that shares a 59% sequence homology to Ara h 2. PMID: 29680589 Ara h 6 and Ara h 2 together were found to be the best predictors for moderate to severe peanut allergy. Both are resistant to thermal processing, gastric acids, and digestive proteases. They also become more stable in the process of roasting. PMID: 26095653
Source: Regenstrief LOINC
LP32397-9 Ab.IgG4
IgG4 is the least common subtype of IgG, and it has a variety of functions. In the context of allergic disease it is thought to have an immune-inhibitory role in preventing anaphylaxis and is commonly known as a "blocking" antibody. IgG4 binding to an allergen can compete with IgE-mediated binding, thereby inhibiting the activation of mast cells and basophils and IgE-mediated presentation to T-cells. Measuring IgG4 and its ratio to IgE has a role in monitoring allergen specific immunotherapy PMID: 26023323. IgG4 is also thought to have a role in autoimmunity and be involved in a less defined entity known as IgG4-Related Disease, a chronic immune-mediated fibroinflammatory disorder that often manifests with tumor-like masses .[https://www.merckmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/igg4-related-disease/igg4-related-disease]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Arachis hypogaea recombinant (rAra h) 6 Ab.IgG4
- Property
- MCnc
- Time
- Pt
- System
- Ser
- Scale
- Qn
- Method
Additional Names
- Short Name
- Peanut (rAra h) 6 IgG4-mCnc
- Display Name
- Peanut (Arachis hypogaea) recombinant (rAra h) 6 IgG4 (S) [Mass/Vol]
- Consumer Name Alpha Get Info
- Peanut recombinant (rAra h) 6 IgG4 antibody
Basic Attributes
- Class
- ALLERGY
- Type
- Laboratory
- First Released
- Version 2.72
- Last Updated
- Version 2.72
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Arachis hypogaea recombinante (rAra h) 6 IgG4: Synonyms: Cuantitativo |
fr-FR | French (France) | Arachide rAra h6 (recombinant) Ac IgG4: |
it-IT | Italian (Italy) | Arachis hypogaea, ricombinante (rAra h) 6 Ab.IgG4: Synonyms: Anticorpi IgG4 anticorpo Arachide (Arachis hypogaea) Concentrazione di Massa Punto nel tempo (episodio) Ricombinante (rAra h) 6 di arachide (Arachis hypog Risposta agli antigeni Siero |
zh-CN | Chinese (China) | 落花生 重组 (rAra h) 6 抗体.IgG4: Synonyms: Ab.IgG4; |
Example Units
Unit | Source |
---|---|
mg/L | Example UCUM Units |
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