LOINC
Version 2.68

LP100616-41-HydroxymidazolamActive

Description

LP100616-4   1-Hydroxymidazolam
1-Hydroxymidazolam is an active metabolite of the drug midazolam (known by the brand names Dormicum, Hypnovel, and Versed). Although the metabolite is active, it is found in much smaller concentrations than the parent. Midazolam is metabolized by cytochrome C450 3A (CYP3A) primarily to 1-Hydroxymidazolam, but also in smaller amounts to 4-Hydroxymedazolam and also the 1,4 Dihydroxy form. Determining the conversion kinetics of midazolam has been proposed for CYP3A phenotyoing (Rapid Commun. Mass Spectrom. 2007; 21: 1531–1540). Source: Regenstrief LOINC

Basic Part Properties

Name
1-Hydroxymidazolam
Type
Component
Created On
2010-04-26
Construct for LOINC Short Name
1OH-midazolam

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP100616-4

Language Variants Get Info

zh-CNChinese (CHINA)
1-羟基咪达唑仑
Synonyms: 1-羟基咪哒唑仑
nl-NLDutch (NETHERLANDS)
1-hydroxymidazolam
et-EEEstonian (ESTONIA)
1-hüdroksümidasolaam
fr-BEFrench (BELGIUM)
1-Hydroxymidazolam
fr-CAFrench (CANADA)
1-Hydroxymidazolam
it-ITItalian (ITALY)
1-Idrossimidazolam
ru-RURussian (RUSSIAN FEDERATION)
1-гидроксимидазолам
es-ESSpanish (SPAIN)
1-Hidroximidazolam
tr-TRTurkish (TURKEY)
1-Hidroksimidazolam