LOINC
Version 2.73

LP14550-5SulfamethoxazoleActive

Description

LP14550-5   Sulfamethoxazole
Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic. It is most often used as part of a synergistic combination with trimethoprim in a 5:1 ratio in co-trimoxazole, which is also known as Bactrim or Septrin. It can be used as an alternative to amoxicillin -based antibiotics to treat sinusitis. Mechanism of action:Sulfonamides are structural anologs and competitive antagonists of para-aminobenzoic acid (PABA). They inhibit normal bacterial utilization of PABA for the synthesis of folic acid, an important metabolite in DNA synthesis. The effects seen are usually bacteriostatic in nature. Folic acid is not synthesized in humans, but is instead a dietary requirement. This allows for the selective toxicity to bacterial cells (or any cell dependent on synthesizing folic acid) over human cells. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Sulfamethoxazole (Wikipedia)

Basic Part Properties

Name
Sulfamethoxazole
Type
Component
Created On
2000-05-04
Construct for LOINC Short Name
Sulfamethoxazole

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP14550-5

Language Variants Get Info

zh-CNChinese (China)
磺胺甲噁唑
Synonyms: SMX;SMZ;新明磺;新诺明;磺胺甲噁唑;磺胺甲基异噁唑;磺胺甲基异恶唑;磺胺甲异唑;磺胺甲恶唑
nl-NLDutch (Netherlands)
sulfamethoxazol
et-EEEstonian (Estonia)
Sulfametoksasool
fr-BEFrench (Belgium)
Sulfaméthoxazole
fr-CAFrench (Canada)
Sulfaméthoxazole
it-ITItalian (Italy)
Sulfametossazolo
ru-RURussian (Russian Federation)
Сульфаметоксазол
es-ESSpanish (Spain)
Sulfametoxazol
tr-TRTurkish (Turkey)
Sulfametoksazol