Alpha 1-antichymotrypsin is an alpha globulin glycoprotein that is a member of the serpin superfamily.
It inhibits the activity of certain enzymes called proteases, such as cathepsin G that is found in neutrophils, and chymases found in mast cells, by cleaving them into a different shape or conformation. This activity protects some tissues, such as the lower respiratory tract, from damage caused by proteolytic enzymes.
This protein is produced in the liver, and is an acute phase protein that is induced during inflammation. Deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.
Alpha 1-antichymotrypsin is also associated with the pathogenesis of Alzheimer's disease as it enhances the formation of amyloid-fibrils in this disease Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia
Basic Part Properties
- Created On
- Construct for LOINC Short Name
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Language Variants Get Info
- zh-CNChinese (CHINA)
Synonyms: A 1 抗凝乳蛋白酶;
A 1 抗胰凝乳蛋白酶; A1 抗凝乳蛋白酶; A1 抗胰凝乳蛋白酶; A1ACT; A-1-抗凝乳蛋白酶; A1-抗凝乳蛋白酶; A-1-抗胰凝乳蛋白酶; A1-抗胰凝乳蛋白酶; ACT; Alpha 1 抗凝乳蛋白酶; Alpha 1 抗胰凝乳蛋白酶; Alpha1 抗凝乳蛋白酶; Alpha1 抗胰凝乳蛋白酶; Alpha1-抗凝乳蛋白酶; Alpha-1-抗胰凝乳蛋白酶; Alpha1-抗胰凝乳蛋白酶; α1 抗凝乳蛋白酶; α1 抗胰凝乳蛋白酶; α1-抗凝乳蛋白酶; α1-抗胰凝乳蛋白酶
- nl-NLDutch (NETHERLANDS)
- et-EEEstonian (ESTONIA)
- fr-BEFrench (BELGIUM)
- fr-CAFrench (CANADA)
- it-ITItalian (ITALY)
- ru-RURussian (RUSSIAN FEDERATION)
- es-ESSpanish (SPAIN)
- tr-TRTurkish (TURKEY)
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