LP14668-5HMB-45Active
Description
LP14668-5 HMB-45
HMB-45 is a monoclonal antibody that reacts against an antigen present in melanocytic tumors such as melanomas, and stands for Human Melanoma Black. It is used in anatomic pathology as a marker for such tumors.
The antibody was generated to an extract of melanoma. It reacts positively against melanocytic tumors but not other tumors, thus demonstrating specificity and sensitivity. The antibody also reacts positively against junctional nevus cells but not intradermal nevi, and against fetal melanocytes but not normal adult melanocytes.
HMB-45 is nonreactive with almost all non-melanoma human malignancies, with the exception of rare tumors showing evidence of melanogenesis (e.g., pigmented schwannoma, clear cell sarcoma) or tumors associated with tuberous sclerosis complex (angiomyolipoma and lymphangiomyoma).
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Source: Wikipedia, Wikipedia
Basic Part Properties
- Name
- HMB-45
- Type
- Component
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- HMB45
LOINC FHIR® API Example - CodeSystem Request Get Info
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP14668-5
Language Variants Get Info
- zh-CNChinese (China)
- HMB-45
- nl-NLDutch (Netherlands)
- HMB-45
- et-EEEstonian (Estonia)
- HMB-45
- fr-BEFrench (Belgium)
- HMB-45
- fr-CAFrench (Canada)
- HMB-45
- it-ITItalian (Italy)
- HMB-45
- ru-RURussian (Russian Federation)
- HMB-45
- es-ESSpanish (Spain)
- HMB-45
- tr-TRTurkish (Turkey)
- HMB-45
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