LOINC
Version 2.72

LP14668-5HMB-45Active

Description

LP14668-5   HMB-45
HMB-45 is a monoclonal antibody that reacts against an antigen present in melanocytic tumors such as melanomas, and stands for Human Melanoma Black. It is used in anatomic pathology as a marker for such tumors.

The antibody was generated to an extract of melanoma. It reacts positively against melanocytic tumors but not other tumors, thus demonstrating specificity and sensitivity. The antibody also reacts positively against junctional nevus cells but not intradermal nevi, and against fetal melanocytes but not normal adult melanocytes.

HMB-45 is nonreactive with almost all non-melanoma human malignancies, with the exception of rare tumors showing evidence of melanogenesis (e.g., pigmented schwannoma, clear cell sarcoma) or tumors associated with tuberous sclerosis complex (angiomyolipoma and lymphangiomyoma). Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

Basic Part Properties

Name
HMB-45
Type
Component
Created On
2000-05-04
Construct for LOINC Short Name
HMB45

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP14668-5

Language Variants Get Info

zh-CNChinese (China)
HMB-45
nl-NLDutch (Netherlands)
HMB-45
et-EEEstonian (Estonia)
HMB-45
fr-BEFrench (Belgium)
HMB-45
fr-CAFrench (Canada)
HMB-45
it-ITItalian (Italy)
HMB-45
ru-RURussian (Russian Federation)
HMB-45
es-ESSpanish (Spain)
HMB-45
tr-TRTurkish (Turkey)
HMB-45