Version 2.73

LP14685-9Myelin basic proteinActive


LP14685-9   Myelin basic protein
Myelin basic protein (MBP) is important in the process of myelination of nerves in the central nervous system (CNS). MBP was initially sequenced in 1979 after isolation from myelin membranes. Since that time, knockout mice deficient in MBP have been developed which showed decreased amounts of CNS myelination and a progressive disorder characterized by tremors, seizures, and early death. The gene for MBP is on chromosome 18; the protein localizes to the CNS and to various cells of the hematopoietic system. The pool of MBP in the central nervous system is very diverse, with several splice variants being expressed and a large number of post-translational modifications on the protein, which include phosphorylation, methylation, deamidation and citrullination. Interest in MBP has centered on its role in demyelinating diseases, particularly multiple sclerosis (MS). Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Myelin basic protein (Wikipedia)

Basic Part Properties

Myelin basic protein
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Language Variants Get Info

zh-CNChinese (China)
Synonyms: MBP;骨磷脂碱性蛋白;髓磷脂碱性蛋白(Myelin Basic Protein,MBP);髓鞘质碱性蛋白
nl-NLDutch (Netherlands)
myeline basic proteïn
fr-BEFrench (Belgium)
Protéine basique de la myéline
fr-CAFrench (Canada)
Protéine basique de la myeline
it-ITItalian (Italy)
Mielina, proteina basica
Synonyms: Proteina basica della mielina
ru-RURussian (Russian Federation)
Миелина основной протеин
Synonyms: Миелина основной белок
es-ESSpanish (Spain)
Proteína básica de la mielina
Synonyms: Миелина основной белок
tr-TRTurkish (Turkey)
Miyelin bazik protein