LP14729-5PHENobarbitalActive
Description
LP14729-5 PHENobarbital
Phenobarbital is an antiepileptic drug first introduced for clinical use in 1912. It is still used to treat most seizures except for absence seizure types. The CYP2C19 enzyme metabolizes phenobarbital to p-hydroxyphenobarbital which is then excreted as glucuronide. Phenobarbital induces secretion of liver enzymes which can impact the efficacy of drugs administered at the same time. The most common side effect of phenobarbital in adults with blood levels greater than 40 mg/L is sedation. Phenobarbital is an active metabolite of primidone and so must also be monitored in patients on primidone.(Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, Seventh Edition; Carl A. Burtis; David E. Bruns)
Source: Regenstrief LOINC
Basic Part Properties
- Name
- PHENobarbital
- Type
- Component
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- PHENobarb
LOINC FHIR® API Example - CodeSystem Request Get Info
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP14729-5
Language Variants Get Info
- zh-CNChinese (CHINA)
- 苯巴比妥
Synonyms: C12H12N2O3;苯巴比妥米那; 鲁米那; 苯基巴比妥; 本巴比妥 - nl-NLDutch (NETHERLANDS)
- fenobarbital
- et-EEEstonian (ESTONIA)
- Fenobarbitaal
- fr-BEFrench (BELGIUM)
- Phénobarbital
- fr-CAFrench (CANADA)
- Phénobarbital
- el-GRGreek (GREECE)
- Φαινοβαρβιτάλη
- it-ITItalian (ITALY)
- Fenobarbital
- ru-RURussian (RUSSIAN FEDERATION)
- Фенобарбитал
- es-ESSpanish (SPAIN)
- Fenobarbital
Synonyms: Luminal;Nirvonal; Phenobarb - tr-TRTurkish (TURKEY)
- Fenobarbital
Synonyms: Nirvonal
LOINC Copyright
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