LOINC
Version 2.72

LP14853-3Varicella zoster virusActive

Description

LP14853-3   Varicella zoster virus
Varicella zoster virus (VZV) is a double-stranded alphaherpesvirus that causes seasonal outbreaks of chickenpox and shingles in non-immunized populations. VZV is highly infectious and is transmitted by contact with the ruptured fluid filled blisters and respiratory secretions of infected individuals. Immunity post infection is usually lifelong though the latent virus inhabits the sensory nerve ganglia where it can reactivate causing shingles when immunity declines with aging.[http://jvi.asm.org/content/88/24/13936.full] In the over fifty strains of VZV that have been sequenced it has been found that a single nucleotide polymorphism occurs about every 100 bases. The patterns of polymorphisms in VZV correlate with different geographical regions of infection and is the basis for the classification of viral clades.[https://grose.lab.uiowa.edu/vzv-genomes-and-evolution] Breuer proposed the nomenclature for the VZV clades as 1-5 with the suspected clades VI and VII to be confirmed later. The geographical regions associated with the seven clades are as follows:
Clades 1 and 3-represent the dominant clades of the circulating VZV in Europe and the Americas
Clades 4 and 5-found in Africa
Clade VI found in France, Italy
Clade VII exclusively isolated in the US
Clade 2-Asia from Korea, Japan, China not found in India, Nepal and Bangladesh where clades 4 and 5 were dominant
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054591/ Source: Regenstrief LOINC

Basic Part Properties

Name
Varicella zoster virus
Type
Component
Created On
2000-05-04
Construct for LOINC Short Name
VZV

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP14853-3

Language Variants Get Info

zh-CNChinese (China)
水痘带状疱疹病毒
Synonyms: HHV-3;VZ;VZV;人类疱疹病毒 3 型;人类疱疹病毒 III 型;带状疱疹;水痘;水痘带状疱疹;水痘病毒;Varicella zoster virus;水痘-带状疱疹病毒
nl-NLDutch (Netherlands)
varicella-zostervirus
Synonyms: Varicella zoster virus
et-EEEstonian (Estonia)
Tuulerõugeviirus
fr-BEFrench (Belgium)
Virus varicelle-zona
Synonyms: VZV
fr-CAFrench (Canada)
Virus varicelle-zona
el-GRGreek (Greece)
Ιός ανεμευλογιάς-έρπητα ζωστήρα
Synonyms: VZV
it-ITItalian (Italy)
Varicella zoster, virus
Synonyms: Virus della varicella zoster
ru-RURussian (Russian Federation)
Varicella zoster вирус
Synonyms: Virus della varicella zoster
es-ESSpanish (Spain)
Virus Varicella zoster
Synonyms: Herpes Varicela
tr-TRTurkish (Turkey)
Varicella zoster virüsü