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LP14903-6Basement membraneActive


LP14903-6   Basement membrane
The basement membrane is a thin sheet of fibers that underlies the epithelium, which lines the cavities and surfaces of organs including skin, or the endothelium, which lines the interior surface of blood vessels.
The primary function of the basement membrane is to anchor down the epithelium to its loose connective tissue underneath. This is achieved by cell-matrix adhesions through substrate adhesion molecules. A group of diseases stemming from improper function of basement membrane zone are united under the name epidermolysis bullosa. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Basement membrane (Wikipedia)

LP14903-6   Basement membrane
A darkly stained mat-like EXTRACELLULAR MATRIX (ECM) that separates cell layers, such as EPITHELIUM from ENDOTHELIUM or a layer of CONNECTIVE TISSUE. The ECM layer that supports an overlying EPITHELIUM or ENDOTHELIUM is called basal lamina. Basement membrane (BM) can be formed by the fusion of either two adjacent basal laminae or a basal lamina with an adjacent reticular lamina of connective tissue. BM, composed mainly of TYPE IV COLLAGEN; glycoprotein LAMININ; and PROTEOGLYCAN, provides barriers as well as channels between interacting cell layers. Source: National Library of Medicine, MeSH 2006

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Basement membrane
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zh-CNChinese (China)
Synonyms: Goodpastures样综合征;Goodpastures病;肺出血-肾炎综合征;肾小球基底膜
nl-NLDutch (Netherlands)
et-EEEstonian (Estonia)
Basaalmembraani vastased
fr-BEFrench (Belgium)
Membrane basale
fr-CAFrench (Canada)
Membrane basale
it-ITItalian (Italy)
Membrana basale
ru-RURussian (Russian Federation)
Базальная мембрана
es-ESSpanish (Spain)
Membrana basal
tr-TRTurkish (Turkey)
Bazal membran
Synonyms: Temel membran; bazal membran