LOINC
Version 2.73

LP14904-4Intercellular substanceActive

Description

LP14904-4   Intercellular substance
Intercellular substance (ICS) antibodies are antibodies to any one of several intercellular antigens, including the desmosomal cadherins desmoglein 1 and 3, and desmocollin 1, 2, and 3, which play a role in cell to cell adhesion. ICS antibodies, especially of type IgG, are associated with paraneoplastic pemphigus (PNP), also known as paraneoplastic autoimmune multiorgan syndrome (PAMS), as well as with other forms of pemphigus including pemphigus foliaceus and pemphigus vulgaris. ICS antibody deposition has a characteristic web- or honeycomb-like fluorescent pattern. [PMID:31214197] Source: Regenstrief LOINC

Basic Part Properties

Name
Intercellular substance
Type
Component
Created On
2000-05-04
Construct for LOINC Short Name
ICS

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP14904-4

Language Variants Get Info

zh-CNChinese (China)
细胞间质
Synonyms: ICS;天泡疮;天疱疮;细胞间结构;细胞间结构(Intercellular structure,ICS);细胞间质(Intercellular Substance,ICS);胞间结构
nl-NLDutch (Netherlands)
intercellulaire substantie
fr-BEFrench (Belgium)
Matière intercellulaire
fr-CAFrench (Canada)
Matière intercellulaire
it-ITItalian (Italy)
Sostanza intercellulare
ru-RURussian (Russian Federation)
Межклеточное вещество
es-ESSpanish (Spain)
Sustancia intercelular
Synonyms: Pénfigo
tr-TRTurkish (Turkey)
Hücreler arası substans