LP14904-4Intercellular substanceActive
Description
LP14904-4 Intercellular substance
Intercellular substance (ICS) antibodies are antibodies to any one of several intercellular antigens, including the desmosomal cadherins desmoglein 1 and 3, and desmocollin 1, 2, and 3, which play a role in cell to cell adhesion. ICS antibodies, especially of type IgG, are associated with paraneoplastic pemphigus (PNP), also known as paraneoplastic autoimmune multiorgan syndrome (PAMS), as well as with other forms of pemphigus including pemphigus foliaceus and pemphigus vulgaris. ICS antibody deposition has a characteristic web- or honeycomb-like fluorescent pattern. [PMID:31214197]
Source: Regenstrief LOINC
Basic Part Properties
- Name
- Intercellular substance
- Type
- Component
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- ICS
LOINC FHIR® API Example - CodeSystem Request Get Info
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP14904-4
Language Variants Get Info
- zh-CNChinese (China)
- 细胞间质
Synonyms: ICS;天泡疮; 天疱疮; 细胞间结构; 细胞间结构(Intercellular structure, ICS); 细胞间质(Intercellular Substance, ICS); 胞间结构 - nl-NLDutch (Netherlands)
- intercellulaire substantie
- fr-BEFrench (Belgium)
- Matière intercellulaire
- fr-CAFrench (Canada)
- Matière intercellulaire
- it-ITItalian (Italy)
- Sostanza intercellulare
- ru-RURussian (Russian Federation)
- Межклеточное вещество
- es-ESSpanish (Spain)
- Sustancia intercelular
Synonyms: Pénfigo - tr-TRTurkish (Turkey)
- Hücreler arası substans
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