Version 2.74


β2-Microglobulin (β2-M) is a low-molecular weight protein that is the light chain of the class I MHC (major histocompatibility complex) antigens. Present in all nucleated cells and almost totally reabsorbed and catabolized by the proximal tubules, it is a marker of immune activation and proximal tubular function and found in nearly all body fluids. Because it accumulates with renal dysfunction and deposits in tissues, β2-M is a cause of dialysis related amyloidosis. Levels are also elevated in conditions such as chronic inflammation, liver disease, renal dysfunction, and some acute viral infections. It is found in many hematological malignancies and thus a valuable treatment monitor and prognostic marker, particularly for multiple myeloma. [Tietz] Source: Regenstrief LOINC

Basic Part Properties

Part Type
Component (Describes the core component or analyte measured)
Created On
Construct for LOINC Short Name
B2 Microglob

LOINC Terminology Service (API) using HL7® FHIR®

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Language Variants

Tag Language Translation
zh-CN Chinese (China) Beta-2-微球蛋白
Synonyms: B2 Microglob;b2-M;Beta 2 微球蛋白;β2-微球蛋白;β2 微球蛋白;β2M
fr-CA French (Canada) Bêta-2-microglobuline
et-EE Estonian (Estonia) Beeta-2-mikroglobuliin
es-ES Spanish (Spain) Beta-2-Microglobulina
it-IT Italian (Italy) Beta-2-Microglobulina
el-GR Greek (Greece) β2-μικροσφαιρίνη
tr-TR Turkish (Turkey) Beta-2-Mikroglobulin
ru-RU Russian (Russian Federation) Бета-2-Микроглобулин
nl-NL Dutch (Netherlands) bèta-2-microglobuline
Synonyms: beta-2-Microglobuline
fr-BE French (Belgium) Béta-2-microglobuline
Synonyms: B2M