LOINC
Version 2.73

LP14974-717-HydroxyprogesteroneActive

Description

LP14974-7   17-Hydroxyprogesterone
17-hydroxyprogesterone (17-OHP) is a steroid that is a member of the adrenal biosynthetic pathway and measured in order to diagnose congenital adrenal hyperplasia (CAH). Classic CAH is suspected when virilisation is seen in females at birth. The diagnosis of CAH in boys can be delayed. CAH is characterized by decreased cortisol as a result of a mutation in the CYP21A2 gene, which encodes the enzyme 21-hydroxylase. Increased blood concentrations of 17-OHP indicate a deficiency in 21-hydroxylase since 17-OHP is the substrate for 21-hydroxylase. Reduced levels of 21-hydroxylase negatively affect the production of cortisol. CAH is among the most frequent genetic disorders in humans. The severity of the physical manifestations are related to the degree of 21-hydroxylase deficiency.[PMID:24711560] Source: Regenstrief LOINC

Basic Part Properties

Name
17-Hydroxyprogesterone
Type
Component
Created On
2000-05-04
Construct for LOINC Short Name
17OHP

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP14974-7

Language Variants Get Info

zh-CNChinese (China)
17-羟孕酮
Synonyms: 17-Alpha-OH 黄体酮;17-Alpha-羟黄体酮;17-OH 孕甾酮;17-OH 孕酮;17-OH 黄体激素;17-OH 黄体酮;17OHP;17-OHP;17-OH-黄体酮;17-α-OH 黄体酮;17-α-羟黄体酮;17-孕酮-4-en-3,20-二酮;17-羟基-黄体酮;17-羟孕甾酮;17-羟黄体酮;17-羟黄体激素
nl-NLDutch (Netherlands)
17-hydroxyprogesteron
et-EEEstonian (Estonia)
17-alfahüdroksüprogesteroon
fr-BEFrench (Belgium)
17-hydroxyprogestérone
fr-CAFrench (Canada)
17-hydroxyprogestérone
el-GRGreek (Greece)
17-Υδροξυπρογεστερόνη
Synonyms: 17 ΟΗ-προγεστερόνη
it-ITItalian (Italy)
17-Idrossiprogesterone
Synonyms: 17 ΟΗ-προγεστερόνη
ru-RURussian (Russian Federation)
17-гидроксипрогестерон
es-ESSpanish (Spain)
17-hidroxiprogesterona
tr-TRTurkish (Turkey)
17-Hidroksiprogesteron